1. Gene
  2. Pf4 - platelet factor 4 Gene

Pf4 - platelet factor 4 Gene

种属: Rattus norvegicus

同用名: PF-4; Pf4a; Cxcl4; RATPF4A

基因 ID: 360918 | 基因类型: protein coding

关于 Pf4

功能概要

Predicted to enable CXCR3 Chemokine Receptor binding activity; chemokine activity; and heparin binding activity. Involved in immune response and protein-containing complex assembly. Located in platelet alpha granule. Part of protein-containing complex. Orthologous to several human genes including PF4 (Platelet Factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Pf4 基因产物(1)

mRNA Protein Name
NM_001007729.2 NP_001007730.1 platelet factor 4 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in immune response IDA
IDA: 通过直接分析推断
12383857 RGD
involved in negative regulation of T-helper 17 cell differentiation IDA
IDA: 通过直接分析推断
24986443 RGD
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
24986443 RGD
involved in protein-containing complex assembly IPI
IPI: 通过物理相互作用推断
12676928 RGD
involved in response to aldosterone IEP
IEP: 通过表达模式推断
29713904 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in platelet alpha granule IDA
IDA: 通过直接分析推断
2379543 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
12676928 RGD
located in vesicle IDA
IDA: 通过直接分析推断
2379543 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

platelet factor 4

C-X-C motif chemokine 4

chemokine (C-X-C motif) ligand 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pf4 NCBI NCBI:5196
Mus musculus Pf4 NCBI NCBI:56744