2. Gene
  3. OGDH - Ogdh oxoglutarate dehydrogenase Gene

OGDH - Ogdh oxoglutarate dehydrogenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: E1o; OGDH-E1

基因 ID: 360975 | 基因类型: protein coding

关于 OGDH

功能概要

Enables chaperone binding activity; heat shock protein binding activity; and oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in several processes, including 2-oxoglutarate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Part of oxoglutarate dehydrogenase complex. Orthologous to human OGDH (oxoglutarate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

OGDH 基因产物(1)

mRNA Protein Name
NM_001017461.1 NP_001017461.1 2-oxoglutarate dehydrogenase complex component E1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heat shock protein binding IPI
IPI: 通过物理相互作用推断
9811814 RGD
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IDA
IDA: 通过直接分析推断
9712727 RGD
enables protein-folding chaperone binding IPI
IPI: 通过物理相互作用推断
9811814 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 2-oxoglutarate metabolic process IDA
IDA: 通过直接分析推断
3571202 RGD
involved in NADH metabolic process IDA
IDA: 通过直接分析推断
9712727 RGD
involved in succinyl-CoA metabolic process IDA
IDA: 通过直接分析推断
9712727 RGD
involved in tricarboxylic acid cycle IDA
IDA: 通过直接分析推断
9712727 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of oxoglutarate dehydrogenase complex IDA
IDA: 通过直接分析推断
3571202 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

2-oxoglutarate dehydrogenase complex component E1

2-oxoglutarate dehydrogenase, mitochondrial

2-oxoglutarate dehydrogenase E1 component, mitochondrial

2-oxoglutarate dehydrogenase, mitochondrial-like

OGDC-E1

alpha-KGDH-E1

alpha-ketoglutarate dehydrogenase

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

oxoglutarate dehydrogenase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12688A Succinyl phosphonate trisodium salt Inhibitor ≥98.0% 否
HY-12688 Succinyl phosphonate Inhibitor / 否
HY-RS09758 OGDH Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17494 Ogdh Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23951 Ogdh Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens OGDH NCBI NCBI:4967
Mus musculus OGDH NCBI NCBI:18293
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