2. Gene
  3. Smarca2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Gene

Smarca2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 361745 | 基因类型: protein coding

关于 Smarca2

功能概要

Enables chromatin binding activity. Involved in spermatid development. Predicted to be located in chromatin; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of SWI/SNF complex; nBAF complex; and npBAF complex. Predicted to be active in nucleus. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2). [provided by Alliance of Genome Resources, Apr 2022]

Smarca2 基因产物(1)

mRNA Protein Name
NM_001004446.1 NP_001004446.1 probable global transcription activator SNF2L2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
15574597 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in spermatid development IEP
IEP: 通过表达模式推断
22215678 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

probable global transcription activator SNF2L2

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-171774 PBRM1/SMARCA2,4-ligand-1 / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-144835 Camibirstat Inhibitor 99.06% Phase 1
Pre-clinical Phase
生物活性分子 (191)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-119374 BRM/BRG1 ATP Inhibitor-1 Inhibitor 99.72% 否
HY-145388 AU-15330 99.89% 否
HY-128359 ACBI1 99.92% 否
HY-12409 PFI-3 Inhibitor 99.63% 否
HY-163410 AU-24118 Degrader 99.10% 否
HY-151623 ACBI2 Inhibitor 99.76% 否
HY-144896 FHT-1015 Inhibitor 98.41% 否
HY-W382038 E3 ligase Ligand 32 99.95% 否
HY-145446 SGC-SMARCA-BRDVIII Inhibitor 99.84% 否
HY-149026 GNE-064 Inhibitor 99.65% 否
HY-153361 YD23 Degrader 98.80% 否
HY-125905 VH032-cyclopropane-F 99.92% 否
HY-149458 FHT-2344 Inhibitor 99.67% 否
HY-156568 SMD-3040 Degrader 99.91% 否
HY-156568B SMD-3040 formate Degrader 99.78% 否
HY-144897 FHT-1204 Inhibitor 99.81% 否
HY-43048 2-(2-((6-Chlorohexyl)oxy)ethoxy)acetic acid 95.0% 否
HY-163926 SMARCA2/4-IN-2 99.27% 否
HY-44012 SMARCA-BD ligand 1 for PROTAC 99.07% 否
HY-44012B SMARCA-BD ligand 1 for PROTAC hydrochloride 99.24% 否
HY-159607 PRT3789 Degrader / 否
HY-44012A SMARCA-BD ligand 1 for PROTAC dihydrochloride 98.08% 否
HY-156568A SMD-3040 TFA Degrader 99.90% 否
HY-168215 YDR1 Degrader / 否
HY-168221 YD54 / 否
HY-W063924 Bpin-Cyclohexene-C-COOEt ≥97.0% 否
HY-148381 A947 Inducer / 否
HY-173333 PROTAC SMARCA2/4 degrader-38 / 否
HY-173351 G-6599 Degrader / 否
HY-122573 Bromodomain inhibitor-13 Inhibitor / 否
HY-122645 SMARCA2-IN-4 Inhibitor / 否
HY-153424 PROTAC SMARCA2 degrader-1 / 否
HY-153425 PROTAC SMARCA2 degrader-2 / 否
HY-159449 PROTAC SMARCA2 degrader-5 Degrader / 否
HY-159450 PROTAC SMARCA2 degrader-6 / 否
HY-159451 PROTAC SMARCA2 degrader-7 Inhibitor / 否
HY-159452 PROTAC SMARCA2/4-degrader-1 / 否
HY-159453 PROTAC SMARCA2/4-degrader-2 / 否
HY-159454 PROTAC SMARCA2/4-degrader-3 / 否
HY-159455 PROTAC SMARCA2/4-degrader-4 Degrader / 否
HY-159456 PROTAC SMARCA2/4-degrader-5 Degrader / 否
HY-159457 PROTAC SMARCA2/4-degrader-6 Degrader / 否
HY-159458 PROTAC SMARCA2/4-degrader-7 / 否
HY-159459 PROTAC SMARCA2/4-degrader-32 / 否
HY-159460 PROTAC SMARCA2/4-degrader-8 Inhibitor / 否
HY-159461 PROTAC SMARCA2/4-degrader-9 Degrader / 否
HY-159462 PROTAC SMARCA2 degrader-10 / 否
HY-159538 COOEt-bicyclo[2.2.2]octane-CHO / 否
HY-159548 Cyclopropane-(S,R,S)-AHPC-CO-cyclohexene-Bpin / 否
HY-159550 (S,R,S)-AHPC-CO-cyclohexene-Bpin / 否
HY-159553 Ac-NH-(S,R,S)-AHPC / 否
HY-159558 (S,R,S)-AHPC-CO-cyclohexane-C-Ph-pyrimidine-diazabicyclo / 否
HY-159575 COOEt-cyclohexane-C-Ph-pyrimidine-diazabicyclo / 否
HY-159592 Piperazine-Pyrimidine-Cyclohexane-COOEt / 否
HY-159593 Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo / 否
HY-159594 Dimethylformamide-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo / 否
HY-159677 E3 Ligase Ligand-linker Conjugate 115 / 否
HY-159678 4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate / 否
HY-159679 E3 Ligase Ligand-linker Conjugate 116 / 否
HY-159680 OMs-PEG2-NHAlloc-PEG2-Boc / 否
HY-159682 3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin / 否
HY-159683 E3 Ligase Ligand-linker Conjugate 117 / 否
HY-159683A E3 Ligase Ligand-linker Conjugate 119 / 否
HY-159684 3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin / 否
HY-159685 E3 Ligase Ligand-linker Conjugate 118 / 否
HY-161881 SMARCA2-IN-9 Inhibitor / 否
HY-161882 PROTAC SMARCA2 degrader-8 / 否
HY-161883 JP-2-249 Degrader / 否
HY-161884 SMARCA2/4-IN-1 Inhibitor / 否
HY-161885 SMARCA2-IN-6 Inhibitor / 否
HY-161886 SMARCA2-IN-7 Inhibitor / 否
HY-161887 SMARCA2-IN-8 Inhibitor / 否
HY-161888 DCSM06 Inhibitor / 否
HY-161889 DCSM06-05 Inhibitor / 否
HY-162245 PROTAC SMARCA2 degrader-3 Inhibitor / 否
HY-162739 SMARCA2-IN-1 Inhibitor / 否
HY-162740 SMARCA2-IN-2 Inhibitor / 否
HY-162741 PROTAC SMARCA2/4-degrader-33 / 否
HY-162742 PROTAC SMARCA2 degrader-16 / 否
HY-162743 PROTAC SMARCA2/4-degrader-29 Degrader / 否
HY-162744 PROTAC SMARCA2/4-degrader-31 Degrader / 否
HY-162745 SMARCA2 degrader-20 / 否
HY-162746 PROTAC SMARCA2 degrader-9 / 否
HY-162747 PROTAC SMARCA2 degrader-17 / 否
HY-162748 PROTAC SMARCA2/4-degrader-30 Degrader / 否
HY-162791 (1s,4s)-C1-Piperidine-C1-cyclohexane-C1 / 否
HY-162792 E3 Ligase Ligand-linker Conjugate 112 / 否
HY-162813 PROTAC SMARCA2/4-degrader-25 / 否
HY-162814 SMARCA2/4-ligand-3 / 否
HY-162815 PROTAC SMARCA2/4-degrader-26 / 否
HY-162834 PROTAC SMARCA2/4-degrader-27 Degrader / 否
HY-162835 PROTAC SMARCA2/4-degrader-28 Degrader / 否
HY-163864 PROTAC SMARCA2/4-degrader-11 / 否
HY-163865 PROTAC SMARCA2 degrader-13 / 否
HY-163866 PROTAC SMARCA2 degrader-14 / 否
HY-163867 PROTAC SMARCA2 degrader-15 / 否
HY-163868 PROTAC SMARCA2/4-degrader-15 Degrader / 否
HY-163869 PROTAC SMARCA2/4-degrader-16 / 否
HY-163870 PROTAC SMARCA2/4-degrader-17 Degrader / 否
HY-163871 PROTAC SMARCA2/4-degrader-18 Degrader / 否
HY-163872 PROTAC SMARCA2/4-degrader-10 Degrader / 否
HY-163873 PROTAC SMARCA2/4-degrader-20 Degrader / 否
HY-163874 PROTAC SMARCA2 degrader-12 / 否
HY-163875 PROTAC SMARCA2/4-degrader-22 / 否
HY-163876 PROTAC SMARCA2/4-degrader-23 / 否
HY-163877 PROTAC SMARCA2/4-degrader-19 Degrader / 否
HY-163932 (S,R,S)-AHPC-O-CF3 / 否
HY-163933 (S,R,S)-AHPC-CO-C-cyclohexane / 否
HY-163934 (S,R,S)-AHPC-phenylacetic acid / 否
HY-163935 (S,R,S)-AHPC-m-Tolylacetic acid / 否
HY-163936 (S,R,S)-AHPC-p-toluic acid / 否
HY-163937 (S,R,S)-AHPC-O-CF3 -CO-cyclohexane / 否
HY-163949 SMARCA2/4-IN-3 / 否
HY-163950 (S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin / 否
HY-163951 (S,R,S)-AHPC-Ac / 否
HY-163952 (S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin / 否
HY-163953 (S,R,S)-AHPC-Ala / 否
HY-163954 (S,R,S)-AHPC-Ala-CO-cyclohexene-Bpin / 否
HY-168222 Thalidomide-PEG1-OTs / 否
HY-168223 Boc-Piperazine-2-F-Ph-CHO / 否
HY-168225 PROTAC SMARCA2/4-degrader-35 / 否
HY-168226 E3 ligase Ligand 34 / 否
HY-168228 E3 Ligase Ligand-linker Conjugate 123 / 否
HY-168229 PROTAC SMARCA2 degrader-27 Degrader / 否
HY-168230 SMARCA2 ligand-9 Ligand / 否
HY-168231 trans-Boc-Piperidine-C-PIP-O-cyclobutane-OH / 否
HY-168232 E3 ligase Ligand 35 / 否
HY-168234 PROTAC SMARCA2 degrader-31 Inhibitor / 否
HY-168235 (S,R,S)-AHPC-Me-amide-C9-acid Degrader / 否
HY-168236 PROTAC SMARCA2 degrader-28 Degrader / 否
HY-168237 SMARCA2 ligand-10 / 否
HY-168238 (4-(3-Bromobenzyl)piperazin-1-yl)(piperidin-4-yl)methanone / 否
HY-168239 Thalidomide-piperidine-CO-piperazine-C-3-Br-Ph / 否
HY-168246 PROTAC SMARCA2 degrader-29 Degrader / 否
HY-168257 PROTAC SMARCA2 degrader-30 Inhibitor / 否
HY-169269 PROTAC SMARCA2 degrader-18 Degrader / 否
HY-169270 PROTAC SMARCA2 degrader-19 Degrader / 否
HY-169271 PROTAC SMARCA2 degrader-20 Degrader / 否
HY-169272 PROTAC SMARCA2 degrader-21 Degrader / 否
HY-169273 PROTAC SMARCA2 degrader-22 Degrader / 否
HY-169274 PROTAC SMARCA2 degrader-23 Degrader / 否
HY-169275 PROTAC SMARCA2 degrader-24 Degrader / 否
HY-169276 PROTAC SMARCA2 degrader-25 / 否
HY-169278 PROTAC SMARCA2 degrader-26 Degrader / 否
HY-169279 PROTAC SMARCA2/4-degrader-34 Degrader / 否
HY-169280 PXR Ligand 2 Ligand / 否
HY-169487 SMARCA2 ligand-12 Inhibitor / 否
HY-169488 SMARCA2 ligand-12-3-methylazetidine Inhibitor / 否
HY-169490 SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid / 否
HY-170343 PROTAC SMARCA2 degrader-32 Degrader / 否
HY-170347 PROTAC SMARCA2/4 degrader-36 Degrader / 否
HY-170348 (S)-(S,R,S,R)-AHPC-Me-N3 / 否
HY-170349 SMARCA2 ligand-11 Ligand / 否
HY-170352 E3 Ligase Ligand-linker Conjugate 150 / 否
HY-170353 E3 ligase Ligand 46 / 否
HY-170354 SMARCA2/4-ligand-4 / 否
HY-170356 E3 Ligase Ligand-linker Conjugate 151 / 否
HY-170824 SMD-3236 Degrader / 否
HY-170826 SMARCA2 ligand-14 Ligand / 否
HY-170827 E3 Ligase Ligand-linker Conjugate 159 / 否
HY-170828 SMD-1087 Degrader / 否
HY-171765 SMARCA2/4-ligand-6 / 否
HY-172117 Boc-methylglycine-C2-bromine / 否
HY-174237 PBRM1/SMARCA2,4 binder-1 / 否
HY-175186 LO-3-62 Degrader / 否
HY-175756 SMARCA2/4 degrader-1 Degrader / 否
HY-175867 PROTAC SMARCA2 degrader-34 Degrader / 否
HY-176797 SMARCA2/4 Ligand-Linker Conjugate 2 / 否
HY-176822 SGC-BRDVIII-NC Inhibitor / 否
HY-400685 SMD-3040 intermediate-2 95.82% 否
HY-44824 SMARCA2 ligand-13 Inhibitor / 否
HY-RS13404 SMARCA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W560922 Piperazine-Ac-OMe / 否
HY-W890392 (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate / 否
HY-159472 SMARCA2/4-ligand-1 / 否
HY-159539 COOEt-spiro[3.3]heptane-CHO / 否
HY-159542 SMARCA2 ligand-6 / 否
HY-159543 (S,R,S)-AHPC-CO-Ph-Ph-CHO / 否
HY-159544 SMARCA2 ligand-7 / 否
HY-159545 SMARCA2/4-ligand-2 / 否
HY-159546 (S,R,S)-AHPC-Me-CO-cyclohexene-Bpin / 否
HY-159549 (S,R,S)-AHPC-CO-C-Cyclohexene-Bpin / 否
HY-159556 Dimethylformamide-(S,R,S)-AHPC / 否
HY-168227 trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc / 否
HY-168233 E3 Ligase Ligand-linker Conjugate 124 / 否
HY-169861 PROTAC SMARCA2/4 degrader-37 Degrader / 否
HY-172446 SMARCA2/4-ligand-5 / 否
HY-172738 E3 Ligase Ligand-linker Conjugate 175 / 否
HY-RS16570 Smarca2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23003 Smarca2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W874018 SMARCA2 ligand-8 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smarca2 NCBI NCBI:6595
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