1. Gene
  2. Fga - fibrinogen alpha chain Gene

Fga - fibrinogen alpha chain Gene

种属: Rattus norvegicus

同用名: Fba5e; Ac1873

基因 ID: 361969 | 基因类型: protein coding

关于 Fga

功能概要

Predicted to enable structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; liver regeneration; and response to peptide hormone. Located in blood microparticle and rough endoplasmic reticulum. Used to study asthma; brain ischemia; disseminated intravascular coagulation; and thrombocytopenia. Biomarker of acute kidney failure; disseminated intravascular coagulation; pancreatitis; pulmonary embolism; and pulmonary emphysema. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; familial visceral amyloidosis; and thrombophilia. Orthologous to human FGA (fibrinogen alpha chain). [provided by Alliance of Genome Resources, Apr 2022]

Fga 基因产物(2)

mRNA Protein Name
NM_001008724.2 NP_001008724.1 fibrinogen alpha chain isoform 1 precursor
NM_052797.1 NP_434684.1 fibrinogen alpha chain isoform 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
6185147 RGD
involved in cellular response to granulocyte colony-stimulating factor IEP
IEP: 通过表达模式推断
9488469 RGD
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
9488469 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
2440878 RGD
involved in envenomation resulting in modulation of blood coagulation in another organism IEP
IEP: 通过表达模式推断
6896326 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
3817019 RGD
involved in positive regulation of smooth muscle cell migration IDA
IDA: 通过直接分析推断
11368999 RGD
involved in response to X-ray IEP
IEP: 通过表达模式推断
4170424 RGD
involved in response to cycloheximide IEP
IEP: 通过表达模式推断
444225 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
20838740 RGD
involved in response to genistein IEP
IEP: 通过表达模式推断
20838740 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
4211972 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
4211972 RGD
involved in response to thyroid hormone IEP
IEP: 通过表达模式推断
4211972 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
6169715 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in blood microparticle IDA
IDA: 通过直接分析推断
22014850 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
24667622 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fibrinogen alpha chain

fibrinogen, A alpha polypeptide

fibrinogen, alpha polypeptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fga NCBI NCBI:2243