2. Gene
  3. Hnrnpa2b1 - heterogeneous nuclear ribonucleoprotein A2/B1 Gene

Hnrnpa2b1 - heterogeneous nuclear ribonucleoprotein A2/B1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: hnRNP; Hnrpa2; Hnrpa2b1

基因 ID: 362361 | 基因类型: protein coding

关于 Hnrnpa2b1

功能概要

Enables DNA Polymerase binding activity and nucleic acid binding activity. Involved in several processes, including chromosome organization; mRNA export from nucleus; and regulation of DNA metabolic process. Located in several cellular components, including chromosome; neuronal ribonucleoprotein granule; and nuclear lumen. Is active in glutamatergic synapse and postsynaptic cytosol. Used to study rheumatoid arthritis. Biomarker of hepatocellular carcinoma; pancreatic carcinoma; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in inclusion body myopathy with Paget disease of bone and frontotemporal dementia and inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 2. Orthologous to human HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpa2b1 基因产物(1)

mRNA Protein Name
NM_001104613.2 NP_001098083.2 heterogeneous nuclear ribonucleoproteins A2/B1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA polymerase binding IPI
IPI: 通过物理相互作用推断
23184978 RGD
enables G-rich strand telomeric DNA binding IDA
IDA: 通过直接分析推断
23184978 RGD
enables RNA binding IDA
IDA: 通过直接分析推断
10567417 RGD
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
9578590 RGD
enables mRNA CDS binding IDA
IDA: 通过直接分析推断
16980303 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16518874 RGD
enables regulatory region RNA binding IDA
IDA: 通过直接分析推断
9578590 RGD
enables single-stranded telomeric DNA binding IDA
IDA: 通过直接分析推断
15659580 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G-quadruplex DNA unwinding IDA
IDA: 通过直接分析推断
23184978 RGD
involved in RNA transport IMP
IMP: 通过突变表型推断
14523087 RGD
involved in lung development IEP
IEP: 通过表达模式推断
9761751 RGD
involved in mRNA export from nucleus IDA
IDA: 通过直接分析推断
9578590 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
10978504 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
14991837 RGD
involved in positive regulation of telomere maintenance via telomere lengthening IDA
IDA: 通过直接分析推断
23184978 RGD
involved in response to mineralocorticoid IEP
IEP: 通过表达模式推断
23139218 RGD
involved in telomere capping IDA
IDA: 通过直接分析推断
15659580 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Cajal body IDA
IDA: 通过直接分析推断
23184978 RGD
located in chromatin IDA
IDA: 通过直接分析推断
12415010 RGD
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
23184978 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
22238095 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
22238095 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12415010 RGD
located in neuronal ribonucleoprotein granule IDA
IDA: 通过直接分析推断
14523087 RGD
located in nuclear matrix IDA
IDA: 通过直接分析推断
23184978 RGD
located in nucleus IDA
IDA: 通过直接分析推断
10567417 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
14991837 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
25286195 RGD
is active in postsynaptic density EXP
EXP: 通过实验结果推断
22238095 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
22238095 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heterogeneous nuclear ribonucleoproteins A2/B1

heterogeneous nuclear ribonucleoprotein A2

heterogeneous nuclear ribonucleoprotein B0a

heterogeneous nuclear ribonucleoprotein B0b

heterogeneous nuclear ribonucleoprotein B1

hnRNP A2 / hnRNP B1

hnRNP A2/B1

nuclear ribonucleoprotein particle A2 prote

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N13009 MO-2097 / 否
HY-RS06262 HNRNPA2B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18110 Hnrnpa2b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24584 Hnrnpa2b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hnrnpa2b1 NCBI NCBI:3181
Mus musculus Hnrnpa2b1 NCBI NCBI:53379
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