2. Gene
  3. Lrp8 - LDL receptor related protein 8 Gene

Lrp8 - LDL receptor related protein 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 362558 | 基因类型: protein coding

关于 Lrp8

功能概要

Enables high-density lipoprotein particle binding activity and Kinesin binding activity. Involved in several processes, including cellular response to cholesterol; cellular response to growth factor stimulus; and cerebral cortex development. Located in several cellular components, including dendrite; neuronal cell body; and postsynaptic density. Part of microtubule associated complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; dementia; myocardial infarction; and schizophrenia. Orthologous to human LRP8 (LDL receptor related protein 8). [provided by Alliance of Genome Resources, Apr 2022]

Lrp8 基因产物(20)

mRNA Protein Name
XM_039111159.1 XP_038967087.1 low-density lipoprotein receptor-related protein 8 isoform X18
XM_006238570.3 XP_006238632.1 low-density lipoprotein receptor-related protein 8 isoform X1
XM_039111149.1 XP_038967077.1 low-density lipoprotein receptor-related protein 8 isoform X3
XM_039111148.1 XP_038967076.1 low-density lipoprotein receptor-related protein 8 isoform X2
XM_006238567.3 XP_006238629.1 low-density lipoprotein receptor-related protein 8 isoform X9
XM_039111152.1 XP_038967080.1 low-density lipoprotein receptor-related protein 8 isoform X7
XM_006238571.3 XP_006238633.1 low-density lipoprotein receptor-related protein 8 isoform X4
XM_039111150.1 XP_038967078.1 low-density lipoprotein receptor-related protein 8 isoform X5
XM_039111151.1 XP_038967079.1 low-density lipoprotein receptor-related protein 8 isoform X6
XM_003749993.4 XP_003750041.1 low-density lipoprotein receptor-related protein 8 isoform X8
XM_039111153.1 XP_038967081.1 low-density lipoprotein receptor-related protein 8 isoform X10
XM_003749992.4 XP_003750040.1 low-density lipoprotein receptor-related protein 8 isoform X11
XM_039111154.1 XP_038967082.1 low-density lipoprotein receptor-related protein 8 isoform X12
XM_039111155.1 XP_038967083.1 low-density lipoprotein receptor-related protein 8 isoform X13
XM_342877.8 XP_342878.5 low-density lipoprotein receptor-related protein 8 isoform X14
XM_039111157.1 XP_038967085.1 low-density lipoprotein receptor-related protein 8 isoform X16
XM_039111158.1 XP_038967086.1 low-density lipoprotein receptor-related protein 8 isoform X17
XM_039111156.1 XP_038967084.1 low-density lipoprotein receptor-related protein 8 isoform X15
XM_006238574.3 XP_006238636.1 low-density lipoprotein receptor-related protein 8 isoform X20
XM_039111160.1 XP_038967088.1 low-density lipoprotein receptor-related protein 8 isoform X19
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables high-density lipoprotein particle binding IDA
IDA: 通过直接分析推断
2993274 RGD
enables kinesin binding IPI
IPI: 通过物理相互作用推断
11238452 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cholesterol IEP
IEP: 通过表达模式推断
19414061 RGD
involved in cellular response to growth factor stimulus IEP
IEP: 通过表达模式推断
8626535 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
20368265 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
20368265 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
10867025 RGD
located in dendrite IDA
IDA: 通过直接分析推断
9822699 RGD
part of microtubule associated complex IDA
IDA: 通过直接分析推断
11238452 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10867025 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low-density lipoprotein receptor-related protein 8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07802 LRP8 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19912 Lrp8 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26413 Lrp8 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrp8 NCBI NCBI:7804
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