Cyp46a1 - cytochrome P450, family 46, subfamily a, polypeptide 1 Gene

种属: Rattus norvegicus

关于 Cyp46a1

功能概要

Predicted to enable Cholesterol 24-hydroxylase activity; heme binding activity; and steroid hydroxylase activity. Predicted to be involved in several processes, including Cholesterol catabolic process; progesterone metabolic process; and regulation of long-term synaptic potentiation. Predicted to act upstream of with a negative effect on protein localization to membrane raft. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum membrane; and postsynapse. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (Cytochrome P450 family 46 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]