2. Gene
  3. HCFC1 - Hcfc1 host cell factor C1 Gene

HCFC1 - Hcfc1 host cell factor C1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: HCF; HCF-1; RGD1563804

基因 ID: 363519 | 基因类型: protein coding

关于 HCFC1

功能概要

Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and transcription coactivator activity. Involved in cellular response to organic cyclic compound and negative regulation of transcription by RNA polymerase II. Located in several cellular components, including axon; dendrite; and nucleus. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Orthologous to human HCFC1 (host cell factor C1). [provided by Alliance of Genome Resources, Apr 2022]

HCFC1 基因产物(2)

mRNA Protein Name
NM_001414734.1 NP_001401663.1 host cell factor 1
NM_001139507.2 NP_001132979.1 host cell factor 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
22383875 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
21909281 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
24250814 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
24250814 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
22383875 RGD
located in dendrite IDA
IDA: 通过直接分析推断
22383875 RGD
located in nuclear chromosome IDA
IDA: 通过直接分析推断
24250814 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

host cell factor 1

C1 factor

host cell factor 1-like

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06042 HCFC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19688 Hcfc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26182 Hcfc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens HCFC1 NCBI NCBI:3054
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