2. Gene
  3. SPI1 - Spi1 Spi-1 proto-oncogene Gene

SPI1 - Spi1 Spi-1 proto-oncogene Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pu.1; Sfpi1

基因 ID: 366126 | 基因类型: protein coding

关于 SPI1

功能概要

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in cellular response to ethanol; negative regulation of transcription, DNA-templated; and positive regulation of transcription, DNA-templated. Located in nucleus. Used to study alcohol use disorder. Biomarker of alcohol use disorder. Orthologous to human SPI1 (Spi-1 proto-oncogene). [provided by Alliance of Genome Resources, Apr 2022]

SPI1 基因产物(1)

mRNA Protein Name
NM_001005892.2 NP_001005892.1 transcription factor PU.1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
10867017 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15688197 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10867017 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to ethanol IEP
IEP: 通过表达模式推断
16272341 RGD
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10867017 RGD
involved in osteoclast differentiation IEP
IEP: 通过表达模式推断
22576626 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
10085160 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
22576626 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor PU.1

SFFV proviral integration 1

hematopoietic transcription factor PU.1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

spleen focus forming virus proviral integration oncogene spi1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13671 SPI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17194 Spi1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23630 Serpina1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23645 Spi1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens SPI1 NCBI NCBI:6688
Mus musculus SPI1 NCBI NCBI:20375
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