1. Gene
  2. Mafa - MAF bZIP transcription factor A Gene

Mafa - MAF bZIP transcription factor A Gene

种属: Rattus norvegicus

同用名: RGD1562627

基因 ID: 366949 | 基因类型: protein coding

关于 Mafa

功能概要

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including Insulin secretion; nitric oxide mediated signal transduction; and response to glucose. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Biomarker of diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A). [provided by Alliance of Genome Resources, Apr 2022]

Mafa 基因产物(1)

mRNA Protein Name
NM_001399773.1 NP_001386702.1 transcription factor MafA
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18042454 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor MafA

pancreatic beta-cell-specific transcriptional activator

v-maf avian musculoaponeurotic fibrosarcoma oncogene A

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A

v-maf muscul

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mafa NCBI NCBI:389692
Macaca fascicularis Mafa NCBI NCBI:102126714
Mus musculus Mafa NCBI NCBI:378435