2. Gene
  3. STIMATE - STIM activating enhancer Gene

STIMATE - STIM activating enhancer Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：STIM 激活增强因子

种属: Homo sapiens

同用名: TMEM110

基因 ID: 375346 | 基因类型: protein coding

关于 STIMATE

Cytogenetic location: 3p21.1 Genomic coordinates (GRCh38): 3:52,836,733-52,897,548 (from NCBI)

This gene has 6 transcripts (splice variants), 194 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 12.1), lung (RPKM 12.0) and 25 other tissues.

功能概要

启用钙通道调节剂活动。参与钙池钙通道活动的激活；使用细胞内钙源的钙介导信号；和钙调神经磷酸酶-NFAT 信号级联的正调节。位于皮质内质网；内质网膜；和内质网质膜接触部位。 [由基因组资源联盟提供，2022 年 4 月]

Enables Calcium Channel regulator activity. Involved in activation of store-operated Calcium Channel activity; calcium-mediated signaling using intracellular calcium source; and positive regulation of calcineurin-NFAT signaling cascade. Located in cortical endoplasmic reticulum; endoplasmic reticulum membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Apr 2022]

STIMATE 基因产物(1)

mRNA Protein Name
NM_198563.5 NP_940965.1 store-operated calcium entry regulator STIMATE
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium channel regulator activity IDA
IDA: 通过直接分析推断
26322679 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26322679 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of store-operated calcium channel activity IDA
IDA: 通过直接分析推断
26322679 GOA
involved in store-operated calcium entry IDA
IDA: 通过直接分析推断
26644574 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cortical endoplasmic reticulum IDA
IDA: 通过直接分析推断
26322679 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
26322679 GOA
located in endoplasmic reticulum-plasma membrane contact site IDA
IDA: 通过直接分析推断
26644574 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STIMATE 蛋白结构

STIMATE

STIMATE: STIMATE family (100 - 220)

  • 0
  • 100
  • 200
  • 294 a.a.
蛋白主名 其他名称

store-operated calcium entry regulator STIMATE

STIM-activating enhancer encoded by TMEM110

关联疾病

疾病名称 别名
Stormorken Syndrome

Thrombocytopathy, Asplenia, And Miosis

Stormorken-Sjaastad-Langslet Syndrome

STRMK

York Platelet Syndrome

Yps

Thrombocytopathy, Asplenia And Miosis

Thrombocytopathy Asplenia Miosis

Thrombocytopathy-Asplenia-Miosis Syndrome

Miosis Disorder
Capgras Syndrome

Capgras Delusion Theory
Cenani-Lenz Syndactyly Syndrome

Syndactyly Type 7

Cenani Syndactylism

Cenani-Lenz Syndactyly

CLSS

Syndactyly Cenani Lenz Type

Cenani-Lenz Syndrome

Syndactyly, Type Vii

Cenani-Lenz Type Syndactyly

Cenani Syndactyly

Syndactyly Type Vii
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13915 STIMATE Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus STIMATE MGD MGI:1921500
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