2. Gene
  3. ENTPD8 - ectonucleoside triphosphate diphosphohydrolase 8 Gene

ENTPD8 - ectonucleoside triphosphate diphosphohydrolase 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：外核苷三磷酸二磷酸水解酶 8

种属: Homo sapiens

同用名: UNQ2492; GLSR2492; E-NTPDase; NTPDase-8

基因 ID: 377841 | 基因类型: protein coding

关于 ENTPD8

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,434,364-137,441,357 (from NCBI)

This gene has 4 transcripts (splice variants), 171 orthologues and 7 paralogues. Biased expression in colon (RPKM 14.4), duodenum (RPKM 11.4) and 6 other tissues.

功能概要

预测可启用鸟苷二磷酸酶活性和尿苷二磷酸酶活性。预测参与核苷二磷酸分解代谢过程。预计在核苷二磷酸生物合成过程和核苷一磷酸生物合成过程的上游或内部起作用。预计是膜的组成部分。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable guanosine-diphosphatase activity and uridine-diphosphatase activity. Predicted to be involved in nucleoside diphosphate catabolic process. Predicted to act upstream of or within nucleoside diphosphate biosynthetic process and nucleoside monophosphate biosynthetic process. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ENTPD8 基因产物(2)

mRNA Protein Name
NM_001033113.2 NP_001028285.1 ectonucleoside triphosphate diphosphohydrolase 8 isoform 1
NM_198585.3 NP_940987.2 ectonucleoside triphosphate diphosphohydrolase 8 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ENTPD8 蛋白结构

GDA1_CD39

GDA1_CD39: GDA1/CD39 (nucleoside phosphatase) family (38 - 454)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 495 a.a.
蛋白主名 其他名称

ectonucleoside triphosphate diphosphohydrolase 8

E-NTPDase 8

关联疾病

疾病名称 别名
Spastic Paraplegia 64, Autosomal Recessive

SPG64

Hereditary Spastic Paraplegia 64

Autosomal Recessive Spastic Paraplegia Type 64

Autosomal Recessive Spastic Paraplegia 64

Paraplegia, Spastic, Type 64, Autosomal Recessive
Vasculogenic Impotence

Impotence, Vasculogenic
Trichomoniasis

Trichomonas Infection

Trichomonas Infections

Disease Due To Trichomonadidae

Infection By Trichomonas

Trichomonadosis

Trichomonas Pruritus

Trichomonosis

Tricomoniasis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04401 ENTPD8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18988 Cant1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ENTPD8 VGNC VGNC:28513
Mus musculus ENTPD8 MGD MGI:1919340
Canis familiaris ENTPD8 VGNC VGNC:40386
Felis catus ENTPD8 VGNC VGNC:61884
Macaca mulatta ENTPD8 VGNC VGNC:72104
Rattus norvegicus ENTPD8 RGD RGD:1561793
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