2. Gene
  3. Lemd3 - LEM domain containing 3 Gene

Lemd3 - LEM domain containing 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Man1

基因 ID: 380664 | 基因类型: protein coding

关于 Lemd3

功能概要

Predicted to enable chromatin DNA binding activity. Acts upstream of or within several processes, including blood vessel endothelial cell migration involved in intussusceptive angiogenesis; regulation of extracellular matrix organization; and skeletal muscle cell differentiation. Located in nuclear envelope. Is expressed in several structures, including allantois; foregut diverticulum endoderm; lateral plate mesoderm; neural plate; and primitive streak. Human ortholog(s) of this gene implicated in Buschke-Ollendorff syndrome. Orthologous to human LEMD3 (LEM domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Lemd3 基因产物(1)

mRNA Protein Name
NM_001081193.2 NP_001074662.2 inner nuclear membrane protein Man1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
16943282 MGI
acts upstream of or within blood vessel endothelial cell migration involved in intussusceptive angiogenesis IMP
IMP: 通过突变表型推断
16943282 MGI
acts upstream of or within nucleus organization IMP
IMP: 通过突变表型推断
16943282 MGI
acts upstream of or within regulation of cell cycle IMP
IMP: 通过突变表型推断
19720741 MGI
acts upstream of or within regulation of extracellular matrix organization IMP
IMP: 通过突变表型推断
16943282 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
19720741 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear envelope IDA
IDA: 通过直接分析推断
10671519 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inner nuclear membrane protein Man1

LEM domain-containing protein 3

integral inner nuclear membrane protein MAN1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07589 LEMD3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22607 Lemd3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29122 Lemd3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lemd3 NCBI NCBI:23592
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