2. Gene
  3. NUGGC - nuclear GTPase, germinal center associated Gene

NUGGC - nuclear GTPase, germinal center associated Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核 GTPase，生发中心相关

种属: Homo sapiens

同用名: SLIPGC; C8orf80; SLIP-GC; HMFN0672

基因 ID: 389643 | 基因类型: protein coding

关于 NUGGC

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:28,021,964-28,083,936 (from NCBI)

This gene has 2 transcripts (splice variants) and 216 orthologues. Biased expression in lymph node (RPKM 5.9), liver (RPKM 3.6) and 9 other tissues.

功能概要

启用 GTPase 活动。参与细胞对脂多糖的反应；细胞凋亡过程的负调控；和调节核细胞周期 DNA 复制。预测位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Enables GTPase activity. Involved in cellular response to lipopolysaccharide; negative regulation of apoptotic process; and regulation of nuclear cell cycle DNA replication. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NUGGC 基因产物(1)

mRNA Protein Name
NM_001010906.2 NP_001010906.1 nuclear GTPase SLIP-GC
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activity IDA
IDA: 通过直接分析推断
19734146 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
19734146 GOA
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
19734146 GOA
involved in regulation of nuclear cell cycle DNA replication IMP
IMP: 通过突变表型推断
19734146 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NUGGC 蛋白结构

Dynamin_N

Dynamin_N: Dynamin family (103 - 323)

  • 0
  • 200
  • 400
  • 600
  • 796 a.a.
蛋白主名 其他名称

nuclear GTPase SLIP-GC

GTPase SLIP-GC

关联疾病

疾病名称 别名
Endometrial Stromal Sarcoma

Ess

Endometrial Stromal Sarcoma, High Grade

Undifferentiated Endometrial Sarcoma

Stromal Sarcoma Of The Corpus Uteri

Sarcoma Endometrial Stromal

Sarcoma, Endometrial Stromal

Undifferentiated Stromal Sarcoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09679 NUGGC Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NUGGC VGNC VGNC:32347
Rattus norvegicus NUGGC RGD RGD:1562099
Felis catus NUGGC VGNC VGNC:63917
Canis familiaris NUGGC VGNC VGNC:44041
Mus musculus NUGGC MGD MGI:2685446
Macaca mulatta NUGGC VGNC VGNC:75497
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z