LAIR2 - leukocyte associated immunoglobulin like receptor 2 Gene

中文名称：白细胞相关免疫球蛋白样受体 2

种属: Homo sapiens

同用名: CD306

关于 LAIR2

功能概要

该基因编码的蛋白质是免疫球蛋白超家族的成员。它通过与白细胞相关免疫球蛋白样受体 1 的相似性得到鉴定，后者是一种调节先天免疫反应的膜结合受体。由该基因座编码的蛋白质是一种可溶性受体，可能在胎盘植入过程中抑制胶原蛋白诱导的血小板聚集和血管形成中发挥作用。该基因映射到 19q13.4 区域，称为白细胞受体簇，其中包含免疫球蛋白超家族中的 29 个基因。已经描述了该基因的可变剪接转录物变体。[RefSeq 提供，2013 年 9 月]

The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]