2. Gene
  3. LALBA - lactalbumin alpha Gene

LALBA - lactalbumin alpha Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：乳清蛋白α

种属: Homo sapiens

同用名: LYZG; HAMLET

基因 ID: 3906 | 基因类型: protein coding

关于 LALBA

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:48,567,684-48,571,845 (from NCBI)

This gene has 2 transcripts (splice variants), 109 orthologues and 8 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码 α-乳清蛋白，一种主要的牛奶蛋白质。 α-乳清蛋白形成乳糖合酶 (LS) 异二聚体的调节亚基，β 1,4-半乳糖基转移酶 (beta4Gal-T1) 形成催化组分。这些蛋白质一起使 LS 能够通过将半乳糖部分转移到葡萄糖来产生乳糖。作为单体，α-乳白蛋白能与钙离子和锌离子强烈结合，并可能具有杀菌或抗肿瘤活性。一种称为 HAMLET 的 α-乳白蛋白的折叠变体可能会诱导肿瘤和未成熟细胞的细胞凋亡。[RefSeq 提供，2008 年 7 月]

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces Apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]

LALBA 基因产物(2)

mRNA Protein Name
NM_001384350.1 NP_001371279.1 alpha-lactalbumin precursor
NM_002289.3 NP_002280.1 alpha-lactalbumin precursor

LALBA 蛋白结构

Lys

Lys: C-type lysozyme/alpha-lactalbumin family (20 - 139)

  • 0
  • 100
  • 142 a.a.
蛋白主名 其他名称

alpha-lactalbumin

lactose synthase B protein

重组 LALBA 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70229 LALBA Protein, Human (HEK293, His) P00709 (K20-L142) ≥95%

LALBA 抗体

目录号 产品名 应用 反应物种
HY-P85667 LALBA Antibody (YA5359) WB, IHC-P, ICC/IF, Human

关联疾病

疾病名称 别名
Milk Allergy

Milk Allergic Reaction

Milk Hypersensitivity

Allergy Milk
Skin Papilloma

Cutaneous Papilloma

Papilloma Of Skin

Papilloma Skin
Cow Milk Allergy

Bos Taurus Milk Allergy

Cow'S Milk Protein Sensitivity
Mastitis

Breast Inflammation

Inflammatory Breast Disease

Inflammatory Disease Of Breast

Inflammation Of Non-Human Mammary Gland

Inflammatory Disorder Of Breast

Mastitis Nos

Acute Mastitis Nos

Acute Nonpuerperal Mastitis

Nonpuerperal Mastitis Nos

Subacute Mastitis Nos
Breast Cystic Hypersecretory Carcinoma

Cystic Hypersecretory Carcinoma Of The Breast

Cystic Hypersecretory Duct Carcinoma Of The Breast
Lipid-Rich Carcinoma
Glycogen-Rich Carcinoma

Doid:0081028
Egg Allergy

Allergy To Eggs

Allergies Egg

Egg Hypersensitivity
Pregnancy Adenoma

Lactating Adenoma
Epilepsy, Juvenile Absence 1

Epilepsy, Juvenile Absence, Susceptibility To, 1

EJA1

JAE1

Juvenile Absence Epilepsy 1

Susceptibility To Juvenile Absence Epilepsy 1

Epilepsy, Juvenile Absence, Susceptibility To, Type 1

Absence Epilepsy
Cystic Basal Cell Carcinoma

Skin Cystic Basal Cell Carcinoma
Adenoid Basal Cell Carcinoma

Skin Adenoid Basal Cell Carcinoma

Basal Cell Carcinoma - Adenoid
Lactose Intolerance

Lactose Malabsorption

Lm - Lactose Malabsorption

Alactasia

Dairy Product Intolerance

Hypolactasia

Milk Sugar Intolerance

Cow Milk Enteropathy

Intolerance Or Malabsorption Of Lactose

Lm - [Lactose Malabsorption]

Milk Intolerance
Fish Allergy

Allergy To Fish
Allergic Disease

Hypersensitivity

Allergic Hypersensitivity Disease

Allergic Condition

Allergic Reaction

Allergic Disposition
Food Allergy

Food Hypersensitivity

Food Allergies

Allergy Food

Food Allergen-Induced Hypersensitivity
Polyposis Syndrome, Hereditary Mixed, 2

HMPS2

Hereditary Mixed Polyposis Syndrome 2

Polyposis Syndrome, Mixed Hereditary 2

Polyposis Syndrome, Hereditary Mixed, Type 2
Celiac Disease 1

Celiac Disease

Coeliac Disease

Celiac Sprue

Celiac Disease, Susceptibility To

Gluten-Sensitive Enteropathy

Nontropical Sprue

Sprue

CELIAC1

Celiac Disease, Susceptibility To, 1

Celiac Sprue 1

Celiac Sprue, Susceptibility To, 1

Gluten-Sensitive Enteropathy 1

Gluten-Sensitive Enteropathy, Susceptibility To, 1

Idiopathic Steatorrhea

Cœliac Disease

Gluten Intolerance

Gluten-Induced Enteropathy

Gluten Enteropathy

Celiac Disease, Susceptibility To, Type 1

Childhood Celiac Disease

Coeliac Rickets

Gee Disease

Gee-Herter Disease

Heubner-Herter Disease

Idiopathic Steatorrhoea

Thaysen'S Disease

Herter Gee Syndrome
Perinatal Necrotizing Enterocolitis

Necrotizing Enterocolitis

Enterocolitis Necrotizing

Enterocolitis, Necrotizing

Necrotizing Enterocolitis In Fetus Or Newborn

Perinatal Necrotising Enterocolitis

Pseudomembranous Enterocolitis In Newborn

Nec
Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07496 LALBA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21621 Lalba Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28139 Lalba Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta LALBA VGNC VGNC:74224
Rattus norvegicus LALBA RGD RGD:2987
Canis familiaris LALBA VGNC VGNC:42563
Felis catus LALBA VGNC VGNC:68002
Bos taurus LALBA VGNC VGNC:30768
Mus musculus LALBA MGD MGI:96742
Others LALBA NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z