2. Gene
  3. FRRS1 - ferric chelate reductase 1 Gene

FRRS1 - ferric chelate reductase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：铁螯合还原酶 1

种属: Homo sapiens

同用名: SDR2; SDFR2

基因 ID: 391059 | 基因类型: protein coding

关于 FRRS1

Cytogenetic location: 1p21.2 Genomic coordinates (GRCh38): 1:99,703,970-99,766,635 (from NCBI)

This gene has 5 transcripts (splice variants), 224 orthologues and 2 paralogues. Broad expression in liver (RPKM 6.9), placenta (RPKM 5.3) and 22 other tissues.

功能概要

细胞色素 b561 (CYB561；MIM 600019) 家族的成员，包括 FRRS1，在三价铁从内体运输到细胞质之前将三价铁还原为亚铁 (Vargas 等人，2003 [PubMed 14499595]) 。[OMIM 提供，2008 年 3 月] ]

Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]

FRRS1 基因产物(2)

mRNA Protein Name
NM_001013660.4 NP_001013682.2 ferric-chelate reductase 1 isoform 1 precursor
NM_001361041.2 NP_001347970.1 ferric-chelate reductase 1 isoform 2 precursor

FRRS1 蛋白结构

Reeler

Reeler: Reeler domain (31 - 156)

DOMON

DOMON: DOMON domain (217 - 331)

  • 0
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  • 200
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  • 500
  • 626 a.a.
蛋白主名 其他名称

ferric-chelate reductase 1

SDR-2

关联疾病

疾病名称 别名
Lice Infestation

Pediculosis

Louse Infestation

Mixed Pediculosis

Lice Infestations

Infestation By Pediculus

Mixed Pediculosis Infestation

Pediculosis + Lice

Pediculosis And Phthirus Infection

Pediculosis And Phthirus Infections

Pediculosis And Phthirus Infestation

Infestation By Anoplura

Pediculus Infestation

Lice Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05110 FRRS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05111 FRRS1L Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus FRRS1 VGNC VGNC:62367
Canis familiaris FRRS1 VGNC VGNC:40985
Rattus norvegicus FRRS1 RGD RGD:1306883
Macaca mulatta FRRS1 VGNC VGNC:72795
Mus musculus FRRS1 MGD MGI:108076
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