2. Gene
  3. ASB18 - ankyrin repeat and SOCS box containing 18 Gene

ASB18 - ankyrin repeat and SOCS box containing 18 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锚蛋白重复和 SOCS 盒 18

种属: Homo sapiens

同用名: ASB-18

基因 ID: 401036 | 基因类型: protein coding

关于 ASB18

This gene has 6 transcripts (splice variants), 109 orthologues and 7 paralogues. Low expression observed in reference dataset.

功能概要

由该基因编码的蛋白质是锚蛋白重复序列和含有 SOCS 盒 (ASB) 的蛋白质家族的成员。它们包含锚蛋白重复序列和 SOCS 框域。 SOCS 盒用于将细胞因子信号转导抑制因子 (SOCS) 蛋白及其结合伙伴与 elongin B 和 C 复合物偶联，可能靶向它们进行降解。[RefSeq 提供，2017 年 2 月]

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Feb 2017]

ASB18 基因产物(1)

mRNA Protein Name
NM_212556.4 NP_997721.2 ankyrin repeat and SOCS box protein 18

ASB18 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (124 - 212)

Ank

Ank: Ankyrin repeat (220 - 249)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (272 - 320)

SOCS_box

SOCS_box: SOCS box (421 - 459)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 466 a.a.
蛋白主名 其他名称

ankyrin repeat and SOCS box protein 18

关联疾病

疾病名称 别名
Kleefstra Syndrome 1

9q Subtelomeric Deletion Syndrome

KLEFS1

Chromosome 9q34.3 Deletion Syndrome

9q- Syndrome

9q34 Deletion Syndrome

Kleefstra Syndrome Due To 9q34 Microdeletion

Kleefstra Syndrome

9q-Syndrome

9qstds

Kleefstra Syndrome Due To 9q Subtelomeric Deletion

Kleefstra Syndrome Due To Del(9)(Q34)

Kleefstra Syndrome Due To Monosomy 9q34

Chromosome 9q Subtelomeric Deletion Syndrome

Kleefstra Syndrome, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01066 ASB18 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ASB18 VGNC VGNC:80141
Canis familiaris ASB18 VGNC VGNC:38162
Mus musculus ASB18 MGD MGI:2655109
Bos taurus ASB18 VGNC VGNC:26195
Rattus norvegicus ASB18 RGD RGD:1310850
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