MAS1 - MAS1 proto-oncogene, G protein-coupled receptor Gene

中文名称：MAS1 原癌基因，G 蛋白偶联受体

种属: Homo sapiens

同用名: MAS; MGRA

关于 MAS1

功能概要

该基因编码 I 类七次跨膜 G 蛋白偶联受体。编码的蛋白质是血管紧张素 (1-7) 的受体，优先与 Gq 蛋白偶联，激活磷脂酶 C 信号通路。编码的蛋白质可能通过介导血管紧张素- (1-7) 的作用在多个过程中发挥作用，包括低血压、平滑肌松弛和心脏保护。[RefSeq 提供，2012 年 5 月]

This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the Phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]