1. Gene
  2. TRIM67 - tripartite motif containing 67 Gene

TRIM67 - tripartite motif containing 67 Gene

中文名称:含三方基序 67

种属: Homo sapiens

同用名: TNL

基因 ID: 440730 | 基因类型: protein coding

关于 TRIM67

Cytogenetic location: 1q42.2 Genomic coordinates (GRCh38): 1:231,162,058-231,221,565 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 80 paralogues. Biased expression in brain (RPKM 4.1) and adrenal (RPKM 0.2).

功能概要

预测可启用锌离子结合活性。预计参与蛋白质定位的调节。预计在 Ras 蛋白信号转导的负调节上游或负调节内起作用;神经元投射发育的正向调节;和泛素依赖性蛋白质分解代谢过程的正调控。预计位于细胞质和细胞骨架中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of protein localization. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; and positive regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

TRIM67 基因产物(3)

mRNA Protein Name
NM_001004342.5 NP_001004342.3 tripartite motif-containing protein 67 isoform 1
NM_001300889.3 NP_001287818.1 tripartite motif-containing protein 67 isoform 2
NM_001410937.1 NP_001397866.1 tripartite motif-containing protein 67 isoform 3

TRIM67 蛋白结构

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (7 - 35)

zf-B_box

zf-B_box: B-box zinc finger (301 - 340)

fn3

fn3: Fibronectin type III domain (526 - 597)

SPRY

SPRY: SPRY domain (649 - 767)

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  • 783 a.a.
蛋白主名 其他名称

tripartite motif-containing protein 67

TRIM9-like protein TNL

直系同源

种属 基因名 来源 基因 ID
Mus musculus TRIM67 MGD MGI:3045323
Macaca mulatta TRIM67 VGNC VGNC:79915
Canis familiaris TRIM67 VGNC VGNC:47834
Bos taurus TRIM67 VGNC VGNC:55996
Rattus norvegicus TRIM67 RGD RGD:1560667