2. Gene
  3. NKX6-1 - NK6 homeobox 1 Gene

NKX6-1 - NK6 homeobox 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NK6 同源框 1

种属: Homo sapiens

同用名: NKX6A; NKX6.1

基因 ID: 4825 | 基因类型: protein coding

关于 NKX6-1

Cytogenetic location: 4q21.23 Genomic coordinates (GRCh38): 4:84,491,985-84,499,292 (from NCBI)

This gene has 2 transcripts (splice variants), 202 orthologues and 13 paralogues. Biased expression in esophagus (RPKM 3.3), thyroid (RPKM 0.9) and 4 other tissues.

功能概要

在胰腺中，NKX6.1 是 β 细胞发育所必需的，并且是一种有效的双功能转录调节因子，可与靶基因 Iype 等人的启动子区域内富含 AT 的序列结合。 (2004) [PubMed 15056733]。[OMIM 提供，2008 年 3 月]

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]

NKX6-1 基因产物(1)

mRNA Protein Name
NM_006168.3 NP_006159.2 homeobox protein Nkx-6.1

NKX6-1 蛋白结构

Homeobox

Homeobox: Homeobox domain (237 - 293)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
蛋白主名 其他名称

homeobox protein Nkx-6.1

NK homeo box, family 6, member A

NKX6-1 抗体

目录号 产品名 应用 反应物种
HY-P81474 NKX6.1 Antibody (YA1219) IHC-P Human

关联疾病

疾病名称 别名
Pancreatic Agenesis

Partial Pancreatic Agenesis

Congenital Pancreatic Agenesis

Partial Agenesis Of The Pancreas

Agenesis, Pancreatic

Pancreatic Agenesis, Congenital
Maturity-Onset Diabetes Of The Young, Type 4

Maturity-Onset Diabetes Of The Young Type 4

MODY4

Mody, Type Iv

Mody Type 4

Mody, Type 4

Maturity-Onset Diabetes Of The Young 4

Mody-4

Diabetes Of The Young, Maturity-Onset, Type 4

Maturity-Onset Diabetes Of The Young, Type Iv
Neonatal Diabetes

Neonatal Diabetes Mellitus

Diabetes Mellitus Syndrome In Newborn Infant

Ndm
Maturity-Onset Diabetes Of The Young, Type 3

Maturity-Onset Diabetes Of The Young Type 3

MODY3

Mody, Type Iii

Mody Type 3

Mody, Type 3

Maturity-Onset Diabetes Of The Young 3

Mody-3

Diabetes Of The Young, Maturity-Onset, Type 3
Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset
Permanent Neonatal Diabetes Mellitus

Pndm

Permanent Diabetes Mellitus Of Infancy

Pdmi

Neonatal Diabetes Mellitus, Permanent
Maturity-Onset Diabetes Of The Young, Type 1

Maturity-Onset Diabetes Of The Young Type 1

MODY1

Mild Juvenile Diabetes Mellitus

Mody, Type I

Diabetes Mellitus Type 2

Mody Type 1

Mody, Type 1

Maturity-Onset Diabetes Of The Young 1

Mody-1

Diabetes Of The Young, Maturity-Onset, Type 1
Pancreatic Cystadenoma

Cystadenoma Of Pancreas
Diabetes Mellitus

Diabetes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09335 NKX6-1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus NKX6-1 VGNC VGNC:78535
Rattus norvegicus NKX6-1 RGD RGD:69318
Bos taurus NKX6-1 VGNC VGNC:32107
Canis familiaris NKX6-1 VGNC VGNC:54334
Macaca mulatta NKX6-1 VGNC VGNC:75356
Mus musculus NKX6-1 MGD MGI:1206039
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