1. Gene
  2. OMG - oligodendrocyte myelin glycoprotein Gene

OMG - oligodendrocyte myelin glycoprotein Gene

中文名称:少突胶质细胞髓鞘糖蛋白

种属: Homo sapiens

同用名: OMGP

基因 ID: 4974 | 基因类型: protein coding

关于 OMG

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,294,647-31,297,239 (from NCBI)

This gene has 4 transcripts (splice variants), 250 orthologues and 10 paralogues. Restricted expression toward brain (RPKM 57.3).

功能概要

预测具有相同的蛋白质结合活性。预计参与神经元投射再生。预计在完整轴突的侧枝发芽调节上游或调节内对损伤做出反应。预测位于质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable identical protein binding activity. Predicted to be involved in neuron projection regeneration. Predicted to act upstream of or within regulation of collateral sprouting of intact axon in response to injury. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OMG 基因产物(1)

mRNA Protein Name
NM_002544.5 NP_002535.3 oligodendrocyte-myelin glycoprotein precursor

OMG 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (25 - 54)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (56 - 95)

LRR_6

LRR_6: Leucine Rich repeat (145 - 158)

LRR_8

LRR_8: Leucine rich repeat (168 - 226)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 440 a.a.
蛋白主名 其他名称

oligodendrocyte-myelin glycoprotein

重组 OMG 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75948 OMGP Protein, Human (HEK293, His) P23515-1 (I25-P416) ≥95%

关联疾病

疾病名称 别名
Neurofibromatosis, Type I

Von Recklinghausen Disease

Neurofibromatosis 1

Neurofibromatosis, Type 1

NF1

Neurofibromatosis, Peripheral Type

Neurofibromatosis Type I

Neurofibromatosis Type 1 Due To Nf1 Mutation Or Intragenic Deletion

Familial Spinal Neurofibromatosis

Fsnf

Peripheral Neurofibromatosis

Von Recklinghausen'S Neurofibromatosis

Von Recklinghausen Disease Due To Nf1 Mutation Or Intragenic Deletion

Neurofibromatosis Peripheral Type

Von Recklinghausen Syndrome

Neurofibromatosis Type 1

Von Recklinghausen Neuropathy

Nf1 - [Neurofibromatosis Type 1]

Recklinghausen Disease

Internuclear Ophthalmoplegia

Ophthalmoplegia Internuclearis

Bielschowsky-Lutz-Cogan Syndrome

Ino - [Internuclear Ophthalmoplegia]

Lhermitte Syndrome

Mlf - [Medial Longitudinal Fasciculus] Syndrome

Internuclear Paralysis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta OMG VGNC VGNC:75584
Mus musculus OMG MGD MGI:106586
Bos taurus OMG VGNC VGNC:50238
Felis catus OMG VGNC VGNC:99315
Rattus norvegicus OMG RGD RGD:1359125
Canis familiaris OMG VGNC VGNC:49934
Susscrofa domestica OMG NCBI
Others OMG NCBI