2. Gene
  3. Cps1 - carbamoyl-phosphate synthase 1 Gene

Cps1 - carbamoyl-phosphate synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: cps; cps-1

基因 ID: 497840 | 基因类型: protein coding

关于 Cps1

功能概要

Enables several functions, including anion binding activity; calcium ion binding activity; and carbamoyl-phosphate synthase (ammonia) activity. Involved in several processes, including cellular response to cAMP; cellular response to oleic acid; and response to peptide hormone. Located in mitochondrial inner membrane. Part of protein-containing complex. Biomarker of fatty liver disease; hypertension; and obesity. Human ortholog(s) of this gene implicated in carbamoyl phosphate synthetase I deficiency disease; persistent fetal circulation syndrome; and vascular disease. Orthologous to human CPS1 (carbamoyl-phosphate synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cps1 基因产物(1)

mRNA Protein Name
NM_017072.2 NP_058768.1 carbamoyl-phosphate synthase [ammonia], mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
11577071 RGD
enables calcium ion binding IPI
IPI: 通过物理相互作用推断
9506839 RGD
enables carbamoyl-phosphate synthase (ammonia) activity IDA
IDA: 通过直接分析推断
3680220 RGD
enables endopeptidase activity IDA
IDA: 通过直接分析推断
15304357 RGD
enables glutamate binding IPI
IPI: 通过物理相互作用推断
8663466 RGD
enables phospholipid binding IDA
IDA: 通过直接分析推断
3680220 RGD
enables phospholipid binding IPI
IPI: 通过物理相互作用推断
1898084 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
17669278 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
17397987 RGD
involved in cellular response to fibroblast growth factor stimulus IEP
IEP: 通过表达模式推断
12832696 RGD
involved in cellular response to glucagon stimulus IEP
IEP: 通过表达模式推断
8460937 RGD
involved in cellular response to oleic acid IEP
IEP: 通过表达模式推断
8985169 RGD
involved in hepatocyte differentiation IEP
IEP: 通过表达模式推断
12939595 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8690412 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
9544996 RGD
involved in monoatomic anion homeostasis IDA
IDA: 通过直接分析推断
4062872 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
2864015 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
11738098 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
6092398 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
19446026 RGD
involved in response to food IEP
IEP: 通过表达模式推断
15481768 RGD
involved in response to glucagon IEP
IEP: 通过表达模式推断
3754512 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
8985169 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17539997 RGD
involved in response to oleic acid IEP
IEP: 通过表达模式推断
8985169 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
1979948 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
14625847 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19135993 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
12840196 RGD
involved in urea cycle IDA
IDA: 通过直接分析推断
3680220 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
3680220 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
14561759 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
17669278 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

carbamoyl-phosphate synthase [ammonia], mitochondrial

CPSase I

carbamoyl-phosphate synthetase 1, mitochondrial

carbamoyl-phosphate synthetase I

carbamyl phosphate synthetase I

carbamyl-phosphate synthetase

carboamyl-phosphate synthetase 1

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0711 Carglumic Acid Activator 99.84% 是
HY-B0711R Carglumic Acid (Standard) Activator / 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-136128 H3B-120 Inhibitor 98.20% 否
HY-RS03115 CPS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-137199 Pro-Phe-Arg-AMC / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cps1 NCBI NCBI:1373
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