2. Gene
  3. MEF2C - Mef2c myocyte enhancer factor 2C Gene

MEF2C - Mef2c myocyte enhancer factor 2C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1563119

基因 ID: 499497 | 基因类型: protein coding

关于 MEF2C

功能概要

Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including cellular response to retinoic acid; dentate gyrus development; and transdifferentiation. Located in nucleus and sarcomere. Used to study myocardial infarction. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Apr 2022]

MEF2C 基因产物(2)

mRNA Protein Name
NM_001399397.1 NP_001386326.1 myocyte-specific enhancer factor 2C isoform 1
NM_001399399.1 NP_001386328.1 myocyte-specific enhancer factor 2C isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
11782488 RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
19654000 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15485823 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
18413674 RGD
involved in cellular response to growth factor stimulus IDA
IDA: 通过直接分析推断
19654000 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
11073966 RGD
involved in cellular response to retinoic acid IDA
IDA: 通过直接分析推断
17568621 RGD
involved in dentate gyrus development IEP
IEP: 通过表达模式推断
18949272 RGD
involved in heart development IEP
IEP: 通过表达模式推断
15486975 RGD
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
19103177 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
19654000 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17696759 RGD
involved in positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
19103177 RGD
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
19654000 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19654000 RGD
involved in response to ischemia IDA
IDA: 通过直接分析推断
19103177 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
20676734 RGD
involved in response to vitamin E IEP
IEP: 通过表达模式推断
16534476 RGD
involved in transdifferentiation IMP
IMP: 通过突变表型推断
23948075 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
19103177 RGD
located in nucleus IDA
IDA: 通过直接分析推断
15862299 RGD
located in sarcomere IDA
IDA: 通过直接分析推断
15862299 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myocyte-specific enhancer factor 2C

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120877 MRT199665 99.74% 否
HY-120877A (R)-MRT199665 98.70% 否
HY-RS08311 MEF2C Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MEF2C NCBI NCBI:4208
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