2. Gene
  3. Huwe1 - HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Gene

Huwe1 - HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: URE-B1

基因 ID: 501546 | 基因类型: protein coding

关于 Huwe1

功能概要

Enables DNA binding activity. Predicted to be involved in several processes, including circadian regulation of gene expression; positive regulation of protein metabolic process; and protein ubiquitination. Located in nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Orthologous to human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Huwe1 基因产物(1)

mRNA Protein Name
NM_001408927.1 NP_001395856.1 E3 ubiquitin-protein ligase HUWE1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
7968380 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
27191843 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
7968380 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase HUWE1

HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase

HECT, UBA and WWE domain-containing protein 1

HECT-type E3 ubiquitin transferase HUWE1

URE-binding protein 1

upstream regulatory element-binding protein 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120929 BI8622 Inhibitor 98.28% 否
HY-120204 BI8626 Inhibitor 98.49% 否
HY-RS06493 HUWE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18391 Huwe1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24872 Huwe1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Huwe1 NCBI NCBI:10075
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