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  3. P2RX5 - purinergic receptor P2X 5 Gene

P2RX5 - purinergic receptor P2X 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：嘌呤能受体 P2X 5

种属: Homo sapiens

同用名: P2X5; LRH-1; P2X5R

基因 ID: 5026 | 基因类型: protein coding

关于 P2RX5

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:3,673,227-3,696,155 (from NCBI)

This gene has 12 transcripts (splice variants), 252 orthologues and 6 paralogues. Biased expression in lymph node (RPKM 41.6), spleen (RPKM 36.1) and 4 other tissues.

功能概要

该基因的产物属于 ATP 嘌呤受体家族。该受体起配体门控离子通道的作用。可变剪接导致多个转录本变体。该基因与邻近的下游基因 TAX1BP3 (Tax1 结合蛋白 3) 之间也存在通读转录。[RefSeq 提供，2011 年 3 月]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]

P2RX5 基因产物(4)

mRNA Protein Name
NM_001204519.2 NP_001191448.1 P2X purinoceptor 5 isoform D
NM_001204520.2 NP_001191449.1 P2X purinoceptor 5 isoform E
NM_002561.4 NP_002552.2 P2X purinoceptor 5 isoform A
NM_175080.3 NP_778255.1 P2X purinoceptor 5 isoform B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP-gated ion channel activity IDA
IDA: 通过直接分析推断
12761352 GOA
enables ligand-gated monoatomic anion channel activity IDA
IDA: 通过直接分析推断
12761352 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chloride transport IDA
IDA: 通过直接分析推断
12761352 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
20223879 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

P2RX5 蛋白结构

P2X_receptor

P2X_receptor: ATP P2X receptor (14 - 330)

P2X_receptor

P2X_receptor: ATP P2X receptor (328 - 364)

  • 0
  • 100
  • 200
  • 300
  • 422 a.a.
蛋白主名 其他名称

P2X purinoceptor 5

ATP receptor subunit

关联疾病

疾病名称 别名
Infiltrative Basal Cell Carcinoma

Skin Infiltrating Basal Cell Carcinoma
Cystinosis

Cystine Storage Disease

Cystine Diathesis

Cystine Disease

Cystinoses

Protein Defect Of Cystin Transport

Cystin Transport, Protein Defect Of

Nephropathic Cystinosis

Protein Defect Of Cystine Transport
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09909 P2RX5 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus P2RX5 RGD RGD:620256
Mus musculus P2RX5 MGD MGI:2137026
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