1. Gene
  2. Plaur - plasminogen activator, urokinase receptor Gene

Plaur - plasminogen activator, urokinase receptor Gene

种属: Rattus norvegicus

同用名: Par; uPAR; Plaur3; uPAR-2; uPAR-3

基因 ID: 50692 | 基因类型: protein coding

关于 Plaur

功能概要

Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in several processes, including epithelial cell differentiation involved in prostate gland development; skeletal muscle tissue regeneration; and spermatogenesis. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Biomarker of chronic obstructive pulmonary disease; myocardial infarction; and status epilepticus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor). [provided by Alliance of Genome Resources, Apr 2022]

Plaur 基因产物(1)

mRNA Protein Name
NM_134352.2 NP_599179.2 urokinase plasminogen activator surface receptor precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial cell differentiation involved in prostate gland development IMP
IMP: 通过突变表型推断
11798065 RGD
involved in mesenchymal cell differentiation IMP
IMP: 通过突变表型推断
11798065 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
11798065 RGD
involved in skeletal muscle tissue regeneration IEP
IEP: 通过表达模式推断
12919869 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
17712486 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

urokinase plasminogen activator surface receptor

U-PAR

plasminogen activator urokinase receptor 3

urinary plasminogen activator receptor 2

urinary plasminogen activator receptor 3

urokinase plasminogen activator receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plaur NCBI NCBI:5329
Macaca fascicularis Plaur NCBI NCBI:102139334
Mus musculus Plaur NCBI NCBI:18793