2. Gene
  3. SERPINA5 - serpin family A member 5 Gene

SERPINA5 - serpin family A member 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：serpin 家族 A 成员 5

种属: Homo sapiens

同用名: PCI; PAI3; PAI-3; PCI-B; PROCI; PLANH3

基因 ID: 5104 | 基因类型: protein coding

关于 SERPINA5

Cytogenetic location: 14q32.13 Genomic coordinates (GRCh38): 14:94,581,426-94,593,118 (from NCBI)

This gene has 12 transcripts (splice variants), 86 orthologues and 36 paralogues. Biased expression in testis (RPKM 322.5), adrenal (RPKM 213.7) and 6 other tissues.

功能概要

由该基因编码的蛋白质是丝氨酸蛋白酶抑制蛋白家族的成员，丝氨酸蛋白酶抑制蛋白家族是一组抑制丝氨酸蛋白酶的蛋白质。该基因是位于 14 号染色体 q 臂上的 serpin 基因簇中的一个。该家族成员是一种糖蛋白，可以抑制多种丝氨酸蛋白酶，包括蛋白 C 和各种纤溶酶原激活剂和激肽释放酶，因此它在止血中发挥多种作用和多个器官的血栓形成。[RefSeq 提供，2012 年 8 月]

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012]

SERPINA5 基因产物(1)

mRNA Protein Name
NM_000624.6 NP_000615.3 plasma serine protease inhibitor preproprotein

SERPINA5 蛋白结构

Serpin

Serpin: Serpin (serine protease inhibitor) (45 - 406)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
蛋白主名 其他名称

plasma serine protease inhibitor

acrosomal serine protease inhibitor

重组 SERPINA5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70975 Serpin A5 Protein, Human (HEK293, His) AAH08915.1 (H20-P406) ≥95%

关联疾病

疾病名称 别名
Pontocerebellar Hypoplasia, Type 14

PCH14

Pontocerebellar Hypoplasia Type 14

Pontocerebellar Hypoplasia 14

Doid:0112325
Thrombosis

Thrombosis Of Blood Vessel
Epilepsy, Idiopathic Generalized 13

Epilepsy, Childhood Absence 4

EIG13

Epilepsy, Idiopathic Generalized, Susceptibility To, 13

Epilepsy, Childhood Absence, Susceptibility To, 4

Idiopathic Generalized Epilepsy 13

Epilepsy, Juvenile Myoclonic, Susceptibility To, 5

Epilepsy, Juvenile Myoclonic 5

ECA4

Juvenile Myoclonic Epilepsy 5

EJM5

Susceptibility To Juvenile Myoclonic Epilepsy 5

Epilepsy, Idiopathic, Generalized, Susceptibility To, Type 13
Spherocytosis, Type 5

Hereditary Spherocytosis Type 5

SPH5

Hs5

Spherocytosis, Hereditary, 5

Hereditary Spherocytosis 5

Spherocytosis 5

Spherocytosis, Hereditary, Type 5
Varicocele

Scrotal Varices

Varicoceles

Varicocele Of Scrotum

Scrotal Varicocele
Malignant Ovarian Cyst
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12701 SERPINA5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SERPINA5 MGD MGI:107817
Bos taurus SERPINA5 VGNC VGNC:53954
Macaca mulatta SERPINA5 VGNC VGNC:77364
Felis catus SERPINA5 VGNC VGNC:68725
Rattus norvegicus SERPINA5 RGD RGD:619817
Canis familiaris SERPINA5 VGNC VGNC:103705
Others SERPINA5 NCBI
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