2. Gene
  3. KCTD3 - potassium channel tetramerization domain containing 3 Gene

KCTD3 - potassium channel tetramerization domain containing 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含钾通道四聚结构域 3

种属: Homo sapiens

同用名: NY-REN-45

基因 ID: 51133 | 基因类型: protein coding

关于 KCTD3

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:215,567,304-215,621,807 (from NCBI)

This gene has 5 transcripts (splice variants), 208 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 47.4), small intestine (RPKM 24.0) and 25 other tissues.

功能概要

该基因编码含有钾通道四聚化结构域 (KCTD) 蛋白家族的成员。该蛋白质家族的成员调节离子通道的生物物理特性。在小鼠中，该蛋白与超极化激活的环核苷酸门控通道复合物 3 相互作用，增强其细胞表面表达和电流密度。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

This gene encodes a member of the Potassium Channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

KCTD3 基因产物(3)

mRNA Protein Name
NM_001319294.2 NP_001306223.1 BTB/POZ domain-containing protein KCTD3 isoform 2
NM_001319295.2 NP_001306224.1 BTB/POZ domain-containing protein KCTD3 isoform 3
NM_016121.5 NP_057205.2 BTB/POZ domain-containing protein KCTD3 isoform 1

KCTD3 蛋白结构

BTB_2

BTB_2: BTB/POZ domain (20 - 105)

  • 0
  • 200
  • 400
  • 600
  • 815 a.a.
蛋白主名 其他名称

BTB/POZ domain-containing protein KCTD3

NY-REN-45 antigen

KCTD3 抗体

目录号 产品名 应用 反应物种
HY-P83392 KCTD3 Antibody (YA3137) WB Human
HY-P86269 KCTD3 Antibody (YA5961) WB Human

关联疾病

疾病名称 别名
Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome

Sen Syndrome

SENS

Scalp Ear Nipple Syndrome

Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

Indian Childhood Cirrhosis
Variegate Porphyria

Porphyria Variegata

Protoporphyrinogen Oxidase Deficiency

VP

Ppox Deficiency

Porphyria, South African Type

Porphyria Variegata, Susceptibility To

Protocoproporphyria

Porphyria Variegate

Porphyria South African Type

Pv

Porphyria, Variegate

Vp - [Variegate Porphyria]
West Syndrome

Infantile Spasms

Infantile Spasms Syndrome

Infantile Spasm

X-Linked Infantile Spasm Syndrome

X-Linked Infantile Spasms

Epileptic Encephalopathy, Early Infantile, 1

Is

Tonic Spasms With Clustering, Arrest Of Psychomotor Development And Hypsarrhythmia On Eeg

West'S Syndrome

Spasms, Infantile

Is -[Infantile Spasm]

Salaam Spasm

Salaam Tic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07195 KCTD3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus KCTD3 MGD MGI:2444629
Macaca mulatta KCTD3 VGNC VGNC:73875
Bos taurus KCTD3 VGNC VGNC:97280
Felis catus KCTD3 VGNC VGNC:63062
Canis familiaris KCTD3 VGNC VGNC:42307
Rattus norvegicus KCTD3 RGD RGD:1310658
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z