2. Gene
  3. ZDHHC3 - zinc finger DHHC-type palmitoyltransferase 3 Gene

ZDHHC3 - zinc finger DHHC-type palmitoyltransferase 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指 DHHC 型棕榈酰转移酶 3

种属: Homo sapiens

同用名: GODZ; DHHC3; DHHC-3; ZNF373

基因 ID: 51304 | 基因类型: protein coding

关于 ZDHHC3

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:44,915,261-44,976,174 (from NCBI)

This gene has 12 transcripts (splice variants), 292 orthologues and 17 paralogues. Ubiquitous expression in testis (RPKM 9.5), skin (RPKM 8.8) and 25 other tissues.

功能概要

启用棕榈酰转移酶活性。参与多个过程，包括 TRAIL 激活的凋亡信号通路；蛋白质定位于膜；和蛋白质定位到光感受器外段。位于高尔基体。 [由基因组资源联盟提供，2022 年 4 月]

Enables palmitoyltransferase activity. Involved in several processes, including TRAIL-activated apoptotic signaling pathway; protein localization to membrane; and protein localization to photoreceptor outer segment. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC3 基因产物(9)

mRNA Protein Name
NM_001135179.2 NP_001128651.1 palmitoyltransferase ZDHHC3 isoform 1
NM_001330761.2 NP_001317690.1 palmitoyltransferase ZDHHC3 isoform 4
NM_001349376.2 NP_001336305.1 palmitoyltransferase ZDHHC3 isoform 5
NM_001349377.2 NP_001336306.1 palmitoyltransferase ZDHHC3 isoform 6
NM_001349378.2 NP_001336307.1 palmitoyltransferase ZDHHC3 isoform 7
NM_001349379.2 NP_001336308.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001349380.2 NP_001336309.1 palmitoyltransferase ZDHHC3 isoform 1
NM_001349381.2 NP_001336310.1 palmitoyltransferase ZDHHC3 isoform 1
NM_016598.3 NP_057682.1 palmitoyltransferase ZDHHC3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables palmitoyltransferase activity IDA
IDA: 通过直接分析推断
21926431 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in TRAIL-activated apoptotic signaling pathway IMP
IMP: 通过突变表型推断
22240897 GOA
involved in lipoprotein localization to membrane IMP
IMP: 通过突变表型推断
22240897 GOA
involved in positive regulation of toll-like receptor 9 signaling pathway IDA
IDA: 通过直接分析推断
38169466 GOA
involved in protein localization to photoreceptor outer segment IDA
IDA: 通过直接分析推断
27613864 GOA
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
22240897 GOA
involved in protein localization to plasma membrane IMP
IMP: 通过突变表型推断
19001095 GOA
involved in protein palmitoylation IDA
IDA: 通过直接分析推断
21926431 GOA
involved in protein palmitoylation IMP
IMP: 通过突变表型推断
19001095 GOA
involved in regulation of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
19001095 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Golgi apparatus IDA
IDA: 通过直接分析推断
27613864 GOA
located in Golgi apparatus IDA
IDA: 通过直接分析推断
16647879 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZDHHC3 蛋白结构

DHHC

DHHC: DHHC palmitoyltransferase (93 - 254)

  • 0
  • 100
  • 200
  • 299 a.a.
蛋白主名 其他名称

palmitoyltransferase ZDHHC3

DHHC1 protein

关联疾病

疾病名称 别名
Neuronal Ceroid Lipofuscinosis

Hereditary Ceroid Lipofuscinosis

Batten Disease

Ncl

Neuronal Ceroid-Lipofuscinoses

Lipofuscinosis, Ceroid, Neuronal

Juvenile Neuronal Ceroid Lipofuscinosis

Cerebromacular Dystrophy

Cerebromacular Degeneration

Ceroid-Lipofuscinosis

Ncl - [Neuronal Ceroid Lipofuscinosis]

Amaurotic Familial Idiocy

Amaurotic Idiocy

Amaurotic Idiot

Neuronal Lipofuscinosis

Pigmentary Retinal Lipoid Neuronal Heredodegeneration
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16021 ZDHHC3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZDHHC3 RGD RGD:1309041
Bos taurus ZDHHC3 VGNC VGNC:37141
Macaca mulatta ZDHHC3 VGNC VGNC:79143
Mus musculus ZDHHC3 MGD MGI:1926134
Canis familiaris ZDHHC3 VGNC VGNC:48591
Felis catus ZDHHC3 VGNC VGNC:67214
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