1. Gene
  2. NGRN - neugrin, neurite outgrowth associated Gene

NGRN - neugrin, neurite outgrowth associated Gene

中文名称:neugrin, neurite outgrowth 相关联

种属: Homo sapiens

同用名: DSC92

基因 ID: 51335 | 基因类型: protein coding

关于 NGRN

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:90,265,663-90,272,211 (from NCBI)

This gene has 3 transcripts (splice variants) and 168 orthologues. Ubiquitous expression in brain (RPKM 111.2), prostate (RPKM 60.9) and 25 other tissues.

功能概要

启用 rRNA 结合活动。参与线粒体翻译的正调控。位于多个细胞成分中,包括细胞间桥;有丝分裂纺锤体;和核体。 [由基因组资源联盟提供,2022 年 4 月]

Enables rRNA binding activity. Involved in positive regulation of mitochondrial translation. Located in several cellular components, including intercellular bridge; mitotic spindle; and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

NGRN 基因产物(1)

mRNA Protein Name
NM_001033088.3 NP_001028260.2 neugrin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables rRNA binding IDA
IDA: 通过直接分析推断
27667664 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial ribosome assembly IMP
IMP: 通过突变表型推断
27667664 GOA
involved in positive regulation of mitochondrial translation IMP
IMP: 通过突变表型推断
27667664 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
27667664 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NGRN 蛋白结构

Neugrin

Neugrin: Neugrin (73 - 291)

  • 0
  • 100
  • 200
  • 291 a.a.
蛋白主名 其他名称

neugrin

mesenchymal stem cell protein DSC92

关联疾病

疾病名称 别名
Deafness, Autosomal Dominant 16

DFNA16

Autosomal Dominant Nonsyndromic Deafness 16

Autosomal Dominant Deafness 16

Deafness, Autosomal Dominant 18

DFNA18

Autosomal Dominant Nonsyndromic Deafness 18

Autosomal Dominant Deafness 18

Deafness, Autosomal Recessive 27

DFNB27

Autosomal Recessive Nonsyndromic Deafness 27

Autosomal Recessive Deafness 27

Deafness, Autosomal Dominant 27

DFNA27

Autosomal Dominant Nonsyndromic Deafness 27

Autosomal Dominant Deafness 27

Deafness, Autosomal Dominant, 27

Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome

Jacobs Syndrome

Arthropathy-Camptodactyly Syndrome

Pericarditis-Arthropathy-Camptodactyly Syndrome

Xyy Syndrome

Pac Syndrome

Cacp Syndrome

CACP

Fibrosing Serositis, Familial

Camptodactyly-Arthropathy-Pericarditis Syndrome

Cap Syndrome

47, Xyy Syndrome

47,Xyy Syndrome

Double Y Syndrome

Camptodactyly-Arthropathy-Coxa-Vara-Pericarditis Syndrome

Hypertrophic Synovitis, Congenital Familial

Congenital Familial Hypertrophic Synovitis

Xyy Karyotype

Y Disomy

Yy Syndrome

Familial Fibrosing Serositis

Disomy Y

Double Y

Camptodactyly Arthropathy Coxa Vara Pericarditis Syndrome

Arthropathy Camptodactyly Syndrome

Camptodactyly Arthropathy Pericarditis Syndrome

Pericarditis Arthropathy Camptodactyly Syndrome

Jacob'S Syndrome

47,Xyy

Cdags Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus NGRN MGD MGI:1933212
Felis catus NGRN VGNC VGNC:80900
Rattus norvegicus NGRN RGD RGD:1583734
Bos taurus NGRN VGNC VGNC:57159
Canis familiaris NGRN VGNC VGNC:59024