1. Gene
  2. Sco1 - SCO1 cytochrome c oxidase assembly protein Gene

Sco1 - SCO1 cytochrome c oxidase assembly protein Gene

种属: Mus musculus

同用名: D11Bwg1310e; 2610001C07Rik

基因 ID: 52892 | 基因类型: protein coding

关于 Sco1

功能概要

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including cyclooxygenase pathway; mitochondrial cytochrome c oxidase assembly; and negative regulation of protein kinase B signaling. Located in mitochondrion. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; liver; submandibular gland primordium; and vascular element. Used to study cytochrome-c oxidase deficiency disease. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sco1 基因产物(1)

mRNA Protein Name
NM_001040026.1 NP_001035115.1 protein SCO1 homolog, mitochondrial
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within copper ion homeostasis IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within cyclooxygenase pathway IMP
IMP: 通过突变表型推断
28973536 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within immune response IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within intracellular copper ion homeostasis IDA
IDA: 通过直接分析推断
28647369 MGI
acts upstream of or within intracellular copper ion homeostasis IMP
IMP: 通过突变表型推断
25683716 MGI
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within intracellular zinc ion homeostasis IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within leukocyte differentiation IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within mitochondrial cytochrome c oxidase assembly IMP
IMP: 通过突变表型推断
25683716 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within negative regulation of cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
28973536 MGI
acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
28647369 MGI
acts upstream of or within negative regulation of proteasomal protein catabolic process IMP
IMP: 通过突变表型推断
25683716 MGI
acts upstream of or within post-transcriptional regulation of gene expression IDA
IDA: 通过直接分析推断
28973536 MGI
acts upstream of proteasomal protein catabolic process IMP
IMP: 通过突变表型推断
25683716 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: 通过突变表型推断
28973536 MGI
acts upstream of or within protein secretion IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within regulation of cytochrome-c oxidase activity IMP
IMP: 通过突变表型推断
28973536 MGI
acts upstream of or within spleen development IMP
IMP: 通过突变表型推断
36301669 MGI
acts upstream of or within thymus development IMP
IMP: 通过突变表型推断
36301669 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
19837698 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein SCO1 homolog, mitochondrial

SCO cytochrome oxidase deficient homolog 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sco1 NCBI NCBI:6341