2. Gene
  3. Dlg3 - discs large MAGUK scaffold protein 3 Gene

Dlg3 - discs large MAGUK scaffold protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dlgh3; SAP102; mKIAA1232

基因 ID: 53310 | 基因类型: protein coding

关于 Dlg3

功能概要

Enables ubiquitin protein Ligase binding activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within establishment of planar polarity and establishment or maintenance of epithelial cell apical/basal polarity. Located in several cellular components, including bicellular tight junction; glutamatergic synapse; and plasma membrane. Part of AMPA glutamate receptor complex. Is expressed in central nervous system and retina. Used to study non-syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 90. Orthologous to human DLG3 (discs large MAGUK scaffold protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Dlg3 基因产物(5)

mRNA Protein Name
NM_001177778.2 NP_001171249.1 disks large homolog 3 isoform 2
NM_001177779.1 NP_001171250.1 disks large homolog 3 isoform 3
NM_001177780.1 NP_001171251.1 disks large homolog 3 isoform 4
NM_001290402.1 NP_001277331.1 disks large homolog 3 isoform 5
NM_016747.4 NP_058027.1 disks large homolog 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12351654 MGI
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
21920314 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within establishment of planar polarity IMP
IMP: 通过突变表型推断
21920314 MGI
acts upstream of or within establishment or maintenance of epithelial cell apical/basal polarity IMP
IMP: 通过突变表型推断
21920314 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: 通过直接分析推断
17046693 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: 通过突变表型推断
17046693 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
22632720 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
21920314 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
21920314 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12351654 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17046693 MGI
located in glutamatergic synapse IDA
IDA: 通过直接分析推断
25429150 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
17046693 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
21920314 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

disks large homolog 3

discs, large homolog 3

synapse-associated protein 102

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03798 DLG3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08624 MPP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20714 Dlg3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27225 Dlg3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlg3 NCBI NCBI:1741
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z