2. Gene
  3. Corin - corin, serine peptidase Gene

Corin - corin, serine peptidase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lrp4

基因 ID: 53419 | 基因类型: protein coding

关于 Corin

功能概要

Enables serine-type endopeptidase activity. Involved in several processes, including peptide hormone processing; regulation of renal sodium excretion; and regulation of systemic arterial blood pressure by atrial natriuretic peptide. Located in cell surface. Is expressed in several structures, including floor plate; heart; lip; phalanx; and skin. Human ortholog(s) of this gene implicated in hypertension and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase). [provided by Alliance of Genome Resources, Apr 2022]

Corin 基因产物(2)

mRNA Protein Name
NM_001122756.1 NP_001116228.1 atrial natriuretic peptide-converting enzyme isoform 2
NM_016869.3 NP_058565.2 atrial natriuretic peptide-converting enzyme isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase activity IMP
IMP: 通过突变表型推断
11884416 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IMP
IMP: 通过突变表型推断
22437503 MGI
involved in peptide hormone processing IMP
IMP: 通过突变表型推断
11884416 MGI
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
22418978 MGI
involved in regulation of renal sodium excretion IMP
IMP: 通过突变表型推断
22418978 MGI
involved in regulation of systemic arterial blood pressure by atrial natriuretic peptide IMP
IMP: 通过突变表型推断
15637153 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
17670789 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

atrial natriuretic peptide-converting enzyme

low density lipoprotein receptor-related protein 4

low density lipoprotein-related protein 4

pro-ANP-converting enzyme

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111048 Corin Inhibitor 98.16% 否
HY-RS03047 CORIN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17975 Corin Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24446 Corin Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Corin NCBI NCBI:10699
Rattus norvegicus Corin NCBI NCBI:289596
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