2. Gene
  3. FXYD3 - FXYD domain containing ion transport regulator 3 Gene

FXYD3 - FXYD domain containing ion transport regulator 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 FXYD 域离子传输调节因子 3

种属: Homo sapiens

同用名: MAT8; PLML

基因 ID: 5349 | 基因类型: protein coding

关于 FXYD3

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,115,823-35,124,324 (from NCBI)

This gene has 14 transcripts (splice variants), 79 orthologues and 6 paralogues. Biased expression in colon (RPKM 158.8), stomach (RPKM 51.0) and 10 other tissues.

功能概要

该基因属于 FXYD 域的一个小家族，包含 Na+/K+ ATP 酶的调节因子，它们共享一个 35 个氨基酸的特征序列域，从序列 PFXYD 开始，并包含 7 个不变氨基酸和 6 个高度保守的氨基酸。该基因编码一种细胞膜蛋白，可调节离子泵和离子通道的功能。该基因也可能在肿瘤进展中发挥作用。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 10 月]

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved Amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

FXYD3 基因产物(14)

mRNA Protein Name
NM_001136007.2 NP_001129479.1 FXYD domain-containing ion transport regulator 3 isoform 3
NM_001136008.2 NP_001129480.1 FXYD domain-containing ion transport regulator 3 isoform 4 precursor
NM_001136009.2 NP_001129481.1 FXYD domain-containing ion transport regulator 3 isoform 5 precursor
NM_001136010.2 NP_001129482.1 FXYD domain-containing ion transport regulator 3 isoform 5 precursor
NM_001136011.2 NP_001129483.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_001136012.2 NP_001129484.1 FXYD domain-containing ion transport regulator 3 isoform 2 precursor
NM_001387349.1 NP_001374278.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_001387350.1 NP_001374279.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_001387352.1 NP_001374281.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_001387353.1 NP_001374282.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_001387354.1 NP_001374283.1 FXYD domain-containing ion transport regulator 3 isoform 6 precursor
NM_001387355.1 NP_001374284.1 FXYD domain-containing ion transport regulator 3 isoform 7
NM_005971.4 NP_005962.1 FXYD domain-containing ion transport regulator 3 isoform 1 precursor
NM_021910.3 NP_068710.1 FXYD domain-containing ion transport regulator 3 isoform 2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FXYD3 蛋白结构

ATP1G1_PLM_MAT8

ATP1G1_PLM_MAT8: ATP1G1/PLM/MAT8 family (25 - 72)

  • 0
  • 87 a.a.
蛋白主名 其他名称

FXYD domain-containing ion transport regulator 3

chloride conductance inducer protein Mat-8

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05167 FXYD3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20024 Fxyd3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26527 Fxyd3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FXYD3 RGD RGD:620825
Mus musculus FXYD3 MGD MGI:107497
Canis familiaris FXYD3 VGNC VGNC:41021
Bos taurus FXYD3 VGNC VGNC:52196
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