2. Gene
  3. Fut8 - fucosyltransferase 8 Gene

Fut8 - fucosyltransferase 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 53618 | 基因类型: protein coding

关于 Fut8

功能概要

Enables alpha-(1->6)-fucosyltransferase activity. Acts upstream of or within several processes, including N-glycan fucosylation; N-glycan processing; and cell surface receptor signaling pathway. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Is expressed in telencephalon. Used to study pulmonary emphysema. Orthologous to human FUT8 (fucosyltransferase 8). [provided by Alliance of Genome Resources, Apr 2022]

Fut8 基因产物(4)

mRNA Protein Name
NM_001252614.1 NP_001239543.1 alpha-(1,6)-fucosyltransferase isoform 1
NM_001252615.1 NP_001239544.1 alpha-(1,6)-fucosyltransferase isoform 2
NM_001252616.1 NP_001239545.1 alpha-(1,6)-fucosyltransferase isoform 3
NM_016893.5 NP_058589.2 alpha-(1,6)-fucosyltransferase isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-(1->6)-fucosyltransferase activity IMP
IMP: 通过突变表型推断
16236725 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within N-glycan fucosylation IMP
IMP: 通过突变表型推断
24619415 MGI
acts upstream of or within N-glycan processing IMP
IMP: 通过突变表型推断
24619415 MGI
acts upstream of or within cell migration IMP
IMP: 通过突变表型推断
17043354 MGI
acts upstream of or within fibroblast migration IMP
IMP: 通过突变表型推断
17043354 MGI
acts upstream of or within integrin-mediated signaling pathway IMP
IMP: 通过突变表型推断
17043354 MGI
acts upstream of or within receptor metabolic process IMP
IMP: 通过突变表型推断
16236725 MGI
acts upstream of or within regulation of cellular response to oxidative stress IMP
IMP: 通过突变表型推断
24619415 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
24619415 MGI
acts upstream of or within respiratory gaseous exchange by respiratory system IMP
IMP: 通过突变表型推断
16236725 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
16236725 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-(1,6)-fucosyltransferase

GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase

GDP-fucose--glycoprotein fucosyltransferase

alpha1-6FucT

glycoprotein 6-alpha-L-fucosyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-155747 FDW028 Inhibitor 99.51% 否
HY-E70157 Fucosyltransferase 8 / 否
HY-170541 FUT8-IN-1 Inhibitor / 否
HY-RS05159 FUT8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17190 Fut8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23641 Fut8 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99010A Bemarituzumab (FUT8-KO) Inhibitor 99.74% 否
HY-P99113A Inebilizumab (FUT8-KO) 97% 否
HY-P9980A Belantamab (FUT-8 KO) 98.10% 否
HY-P9977A Amivantamab (FUT8-KO) Inhibitor 98% 否
HY-P99406A Petosemtamab (FUT8-KO) / 否
HY-P99653A Ianalumab (FUT8-KO) Inhibitor / 否
HY-P9991A Osemitamab (FUT8-KO) / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fut8 NCBI NCBI:2530
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