KCNK10 - potassium two pore domain channel subfamily K member 10 Gene

中文名称：钾二孔域通道亚科 K 成员 10

种属: Homo sapiens

同用名: TREK2; TREK-2; K2p10.1; PPP1R97

关于 KCNK10

功能概要

由该基因编码的蛋白质属于含有两个成孔 P 结构域的钾通道蛋白家族。该通道是一个开放式整流器，主要在生理 K+ 浓度下传递外向电流，并受到花生四烯酸的强烈刺激，并在较小程度上受到膜拉伸、细胞内酸化和全身麻醉的刺激。已经为该基因鉴定了几种编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2008 年 9 月]

The protein encoded by this gene belongs to the family of Potassium Channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]