1. Gene
  2. Arl6ip1 - ADP-ribosylation factor-like 6 interacting protein 1 Gene

Arl6ip1 - ADP-ribosylation factor-like 6 interacting protein 1 Gene

种属: Mus musculus

同用名: AIP-6; ARMER; Aip-1; Arl6ip; mKIAA0069

基因 ID: 54208 | 基因类型: protein coding

关于 Arl6ip1

功能概要

Predicted to enable identical protein binding activity. Involved in positive regulation of L-glutamate import across plasma membrane. Acts upstream of or within cotranslational protein targeting to membrane. Located in cytosol and endoplasmic reticulum. Is integral component of membrane. Part of Sec61 translocon complex. Is expressed in several structures, including central nervous system; genitourinary system; retina; and stomach. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Arl6ip1 基因产物(1)

mRNA Protein Name
NM_019419.2 NP_062292.1 ADP-ribosylation factor-like protein 6-interacting protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10508919 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cotranslational protein targeting to membrane IDA
IDA: 通过直接分析推断
10508919 MGI
involved in positive regulation of L-glutamate import across plasma membrane IDA
IDA: 通过直接分析推断
18684713 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Sec61 translocon complex IDA
IDA: 通过直接分析推断
10508919 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10995579 MGI
located in cytosol IDA
IDA: 通过直接分析推断
10508919 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
18684713 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
18684713 MGI
located in membrane IDA
IDA: 通过直接分析推断
10995579 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ADP-ribosylation factor-like protein 6-interacting protein 1

ADP-ribosylation-like factor 6 interacting protein

ARL-6-interacting protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arl6ip1 NCBI NCBI:23204