2. Gene
  3. SLC12A3 - Slc12a3 solute carrier family 12 member 3 Gene

SLC12A3 - Slc12a3 solute carrier family 12 member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: NCC; TSC

基因 ID: 54300 | 基因类型: protein coding

关于 SLC12A3

功能概要

Enables enzyme binding activity and sodium:chloride symporter activity. Involved in chloride transport and sodium ion transmembrane transport. Located in apical plasma membrane and vesicle. Human ortholog(s) of this gene implicated in Gitelman syndrome and essential hypertension. Orthologous to human SLC12A3 (solute carrier family 12 member 3). [provided by Alliance of Genome Resources, Apr 2022]

SLC12A3 基因产物(1)

mRNA Protein Name
NM_019345.4 NP_062218.3 solute carrier family 12 member 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
11832422 RGD
enables sodium ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
16275913 RGD
enables sodium:chloride symporter activity IDA
IDA: 通过直接分析推断
10894798 RGD
enables sodium:chloride symporter activity IMP
IMP: 通过突变表型推断
8021284 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chloride transport IMP
IMP: 通过突变表型推断
8021284 RGD
involved in sodium ion transmembrane transport IDA
IDA: 通过直接分析推断
16275913 RGD
involved in sodium ion transport IDA
IDA: 通过直接分析推断
16887815 RGD
involved in sodium ion transport IMP
IMP: 通过突变表型推断
8021284 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16554416 RGD
is active in plasma membrane IDA
IDA: 通过直接分析推断
16887815 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
16275913 RGD
located in vesicle IDA
IDA: 通过直接分析推断
16554416 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

solute carrier family 12 member 3

Na-Cl symporter

solute carrier family 12 (sodium/chloride transporter), member 3

solute carrier family 12 (sodium/chloride transporters), member 3

thiazide-sensitive Na-Cl cotransporter

thiazide-sensitive sodium-chloride cotransporter

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B1477 Clopamide Inhibitor 99.0% 否
HY-RS12998 SLC12A3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18580 Slc12a3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25065 Slc12a3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens SLC12A3 NCBI NCBI:6559
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z