1. Gene
  2. Asah2 - N-acylsphingosine amidohydrolase 2 Gene

Asah2 - N-acylsphingosine amidohydrolase 2 Gene

种属: Mus musculus

基因 ID: 54447 | 基因类型: protein coding

关于 Asah2

功能概要

Enables N-acylsphingosine amidohydrolase activity. Involved in lipid digestion and sphingolipid metabolic process. Located in caveola; extracellular space; and mitochondrion. Is integral component of plasma membrane. Orthologous to several human genes including ASAH2B (N-acylsphingosine amidohydrolase 2B). [provided by Alliance of Genome Resources, Apr 2022]

Asah2 基因产物(1)

mRNA Protein Name
NM_018830.1 NP_061300.1 neutral ceramidase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acylsphingosine amidohydrolase activity IDA
IDA: 通过直接分析推断
10652340 MGI
enables N-acylsphingosine amidohydrolase activity IMP
IMP: 通过突变表型推断
21613224 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12921776 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ceramide biosynthetic process IMP
IMP: 通过突变表型推断
21613224 MGI
involved in ceramide catabolic process IDA
IDA: 通过直接分析推断
10652340 MGI
involved in ceramide catabolic process IMP
IMP: 通过突变表型推断
16126722 MGI
involved in lipid digestion IMP
IMP: 通过突变表型推断
16380386 MGI
involved in sphingosine biosynthetic process IDA
IDA: 通过直接分析推断
10652340 MGI
involved in sphingosine biosynthetic process IMP
IMP: 通过突变表型推断
16126722 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
12921776 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
16126722 MGI
located in membrane IDA
IDA: 通过直接分析推断
10753931 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
21613224 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12921776 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neutral ceramidase

N-CDase

NCDase

acylsphingosine deacylase 2

neutral/alkaline ceramidase

重组 Asah2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76735 ASAH2 Protein, Mouse (HEK293, His) Q9JHE3/NP_061300.1 (T34-T756) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asah2 NCBI NCBI:56624