2. Gene
  3. ETAA1 - ETAA1 activator of ATR kinase Gene

ETAA1 - ETAA1 activator of ATR kinase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ATR 激酶的 ETAA1 激活因子

种属: Homo sapiens

同用名: ETAA16

基因 ID: 54465 | 基因类型: protein coding

关于 ETAA1

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:67,397,333-67,412,089 (from NCBI)

This gene has 4 transcripts (splice variants) and 230 orthologues. Ubiquitous expression in thyroid (RPKM 6.6), endometrium (RPKM 6.0) and 25 other tissues.

功能概要

启用蛋白质丝氨酸/苏氨酸激酶激活剂活性。参与多个过程，包括蛋白丝氨酸/苏氨酸激酶活性的正调节； DNA 损伤检查点的调节；和复制叉处理。位于胞质溶胶中；核复制叉；和核质。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activator activity. Involved in several processes, including positive regulation of protein serine/threonine kinase activity; regulation of DNA damage checkpoint; and replication fork processing. Located in cytosol; nuclear replication fork; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ETAA1 基因产物(1)

mRNA Protein Name
NM_019002.4 NP_061875.2 ewing's tumor-associated antigen 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27723717 GOA
enables protein serine/threonine kinase activator activity IDA
IDA: 通过直接分析推断
27723717 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
27723717 GOA
involved in mitotic G2/M transition checkpoint IDA
IDA: 通过直接分析推断
30139873 GOA
involved in positive regulation of protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
27723717 GOA
involved in regulation of DNA damage checkpoint IDA
IDA: 通过直接分析推断
27723717 GOA
involved in replication fork processing IDA
IDA: 通过直接分析推断
27723717 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear replication fork IDA
IDA: 通过直接分析推断
27723717 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ETAA1 蛋白结构

ETAA1

ETAA1: Ewing's tumour-associated antigen 1 homologue (76 - 648)

ETAA1

ETAA1: Ewing's tumour-associated antigen 1 homologue (648 - 913)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 926 a.a.
蛋白主名 其他名称

ewing's tumor-associated antigen 1

ETAA1, ATR kinase activator

ETAA1 抗体

目录号 产品名 应用 反应物种
HY-P83036 ETAA1 Antibody (YA2781) WB Human

关联疾病

疾病名称 别名
Immunodeficiency 26

Severe Combined Immunodeficiency Due To Dna-Pkcs Deficiency

Scid Due To Dna-Pkcs Deficiency

Imd26

Immunodeficiency 26, With Or Without Neurologic Abnormalities
Restless Legs Syndrome

Wed

Willis-Ekbom Disease

Restless Leg Syndrome

Ekbom Syndrome

Wittmaack-Ekbom Syndrome

Willis Ekbom Disease

Ekbom'S Syndrome

Rls

Restless Legs

Restless Legs Syndrome, Susceptibility To
Seckel Syndrome

Microcephalic Primordial Dwarfism

Bird-Headed Dwarfism

Harper'S Syndrome

Virchow-Seckel Dwarfism

Nanocephalic Dwarfism

Sckl

Seckel-Type Dwarfism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04550 ETAA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22495 Etaa1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29018 Etaa1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ETAA1 RGD RGD:1587340
Macaca mulatta ETAA1 VGNC VGNC:106157
Bos taurus ETAA1 VGNC VGNC:28616
Canis familiaris ETAA1 VGNC VGNC:40486
Felis catus ETAA1 VGNC VGNC:61974
Mus musculus ETAA1 MGD MGI:1915395
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z