1. Gene
  2. Cfhr2 - complement factor H-related 2 Gene

Cfhr2 - complement factor H-related 2 Gene

种属: Mus musculus

同用名: FHR-B; Cfhrb_4/2

基因 ID: 545366 | 基因类型: protein coding

关于 Cfhr2

功能概要

Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in age related macular degeneration 1 and atypical hemolytic-uremic syndrome. Orthologous to several human genes including CFHR3 (Complement Factor H Related 3). [provided by Alliance of Genome Resources, Apr 2022]

Cfhr2 基因产物(1)

mRNA Protein Name
NM_001025575.2 NP_001020746.1 complement factor H-related protein B precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables complement component C3b binding IPI
IPI: 通过物理相互作用推断
17028856 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
17028856 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17028856 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

complement factor H-related protein B

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfhr2 NCBI NCBI:3080