2. Gene
  3. Calcrl - calcitonin receptor-like Gene

Calcrl - calcitonin receptor-like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CRLR

基因 ID: 54598 | 基因类型: protein coding

关于 Calcrl

功能概要

Enables Calcitonin gene-related peptide receptor activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; heart development; and positive regulation of smooth muscle cell proliferation. Predicted to be located in endoplasmic reticulum; endosome; and lysosome. Predicted to be part of CGRP Receptor complex and Adrenomedullin receptor complex. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion and lung epithelium. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CALCRL (Calcitonin receptor like receptor). [provided by Alliance of Genome Resources, Apr 2022]

Calcrl 基因产物(1)

mRNA Protein Name
NM_018782.2 NP_061252.2 calcitonin gene-related peptide type 1 receptor precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcitonin gene-related peptide receptor activity IGI
IGI: 通过遗传相互作用推断
8582325 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
8582325 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
16537897 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
16537897 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16537897 MGI
acts upstream of or within positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
16537897 MGI
acts upstream of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
16537897 MGI
acts upstream of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
16537897 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcitonin gene-related peptide type 1 receptor

CGRP type 1 receptor

calcitonin receptor-like receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01835 CALCRL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20140 Calcrl Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26644 Calcrl Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calcrl NCBI NCBI:10203
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