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  2. Paf1 - Paf1, RNA polymerase II complex component Gene

Paf1 - Paf1, RNA polymerase II complex component Gene

种属: Mus musculus

同用名: 5730511K23Rik

基因 ID: 54624 | 基因类型: protein coding

关于 Paf1

功能概要

Enables chromatin binding activity. Involved in several processes, including cellular response to lipopolysaccharide; endodermal cell fate commitment; and negative regulation of transcription by RNA polymerase II. Part of Cdc73/Paf1 complex. Is expressed in cerebral cortex; early conceptus; and genitourinary system. Orthologous to human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]

Paf1 基因产物(1)

mRNA Protein Name
NM_019458.3 NP_062331.2 RNA polymerase II-associated factor 1 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
22252316 MGI
contributes to protein binding IPI
IPI: 通过物理相互作用推断
27749823 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22252316 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
17911113 MGI
involved in endodermal cell fate commitment IMP
IMP: 通过突变表型推断
19345177 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19345177 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
19345177 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cdc73/Paf1 complex IPI
IPI: 通过物理相互作用推断
27749823 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

RNA polymerase II-associated factor 1 homolog

Paf1, RNA polymerase II associated factor, homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Paf1 NCBI NCBI:54623