1. Gene
  2. BTG4 - BTG anti-proliferation factor 4 Gene

BTG4 - BTG anti-proliferation factor 4 Gene

中文名称:BTG 抗增殖因子 4

种属: Homo sapiens

同用名: PC3B; APRO3; OOMD8

基因 ID: 54766 | 基因类型: protein coding

关于 BTG4

Cytogenetic location: 11q23.1 Genomic coordinates (GRCh38): 11:111,383,826-111,514,725 (from NCBI)

This gene has 5 transcripts (splice variants), 194 orthologues, 3 paralogues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 4.9).

功能概要

该基因编码的蛋白质是 BTG/Tob 家族的成员。该家族具有结构相关的蛋白质,这些蛋白质似乎具有抗增殖特性。这种编码的蛋白质可以诱导细胞周期中的 G1 期停滞。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]

BTG4 基因产物(4)

mRNA Protein Name
NM_001367974.1 NP_001354903.1 protein BTG4 isoform 2
NM_001367975.1 NP_001354904.1 protein BTG4 isoform 2
NM_001367976.1 NP_001354905.1 protein BTG4 isoform 3
NM_017589.4 NP_060059.1 protein BTG4 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32502391 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BTG4 蛋白结构

BTG

BTG: BTG family (1 - 117)

  • 0
  • 100
  • 200
  • 223 a.a.
蛋白主名 其他名称

protein BTG4

B-cell translocation gene 4

关联疾病

疾病名称 别名
Oocyte Maturation Defect 8

OOMD8

Infertility
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus BTG4 MGD MGI:1860140
Canis familiaris BTG4 VGNC VGNC:53306
Felis catus BTG4 VGNC VGNC:81909
Bos taurus BTG4 VGNC VGNC:26600
Rattus norvegicus BTG4 RGD RGD:1308809
Macaca mulatta BTG4 VGNC VGNC:70305