1. Gene
  2. ZSCAN2 - zinc finger and SCAN domain containing 2 Gene

ZSCAN2 - zinc finger and SCAN domain containing 2 Gene

中文名称:含锌指和 SCAN 结构域 2

种属: Homo sapiens

同用名: ZFP29; ZNF854

基因 ID: 54993 | 基因类型: protein coding

关于 ZSCAN2

This gene has 15 transcripts (splice variants), 95 orthologues and 38 paralogues. Ubiquitous expression in fat (RPKM 2.7), testis (RPKM 2.7) and 25 other tissues.

功能概要

该基因编码的蛋白质含有数个拷贝的锌指基序,通常存在于转录调节蛋白中。小鼠研究表明,该基因在胚胎发育过程中表达,特别是在成年小鼠的睾丸中,表明它可能在调节生殖细胞基因方面发挥作用。该基因的可变剪接导致编码不同亚型的几种转录变体。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

ZSCAN2 基因产物(3)

mRNA Protein Name
NM_001007072.2 NP_001007073.1 zinc finger and SCAN domain-containing protein 2 isoform 3
NM_017894.6 NP_060364.4 zinc finger and SCAN domain-containing protein 2 isoform 2
NM_181877.4 NP_870992.2 zinc finger and SCAN domain-containing protein 2 isoform 1

ZSCAN2 蛋白结构

SCAN

SCAN: SCAN domain (54 - 136)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (222 - 244)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (264 - 289)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (292 - 317)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (320 - 345)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (348 - 373)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (376 - 400)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (405 - 429)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (432 - 456)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (461 - 484)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (488 - 512)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (517 - 541)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (545 - 568)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (575 - 597)

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  • 614 a.a.
蛋白主名 其他名称

zinc finger and SCAN domain-containing protein 2

zfp-29

关联疾病

疾病名称 别名
Fanconi Anemia, Complementation Group G

Fanconi Anemia Complementation Group G

FANCG

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ZSCAN2 VGNC VGNC:49770
Rattus norvegicus ZSCAN2 RGD RGD:1584548
Bos taurus ZSCAN2 VGNC VGNC:37375
Macaca mulatta ZSCAN2 VGNC VGNC:79298
Mus musculus ZSCAN2 MGD MGI:99176