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  2. LAMTOR1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

LAMTOR1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

中文名称:晚期内体/溶酶体衔接子、MAPK 和 MTOR 激活子 1

种属: Homo sapiens

同用名: p18; PDRO; C11orf59; p27RF-Rho; Ragulator1

基因 ID: 55004 | 基因类型: protein coding

关于 LAMTOR1

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:72,097,292-72,103,297 (from NCBI)

This gene has 8 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in thyroid (RPKM 58.6), adrenal (RPKM 40.5) and 25 other tissues.

功能概要

启用 GTPase 绑定活动。有助于胍基核苷酸交换因子活性和分子接头活性。参与多个过程,包括胆固醇稳态; TOR 信号的正调控;和调节胆固醇运输。位于溶酶体中。 Ragulator 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including Cholesterol homeostasis; positive regulation of TOR signaling; and regulation of Cholesterol transport. Located in lysosome. Part of Ragulator complex. [provided by Alliance of Genome Resources, Apr 2022]

LAMTOR1 基因产物(1)

mRNA Protein Name
NM_017907.3 NP_060377.1 ragulator complex protein LAMTOR1

LAMTOR1 蛋白结构

LAMTOR

LAMTOR: Late endosomal/lysosomal adaptor and MAPK and MTOR activator (16 - 88)

  • 0
  • 100
  • 161 a.a.
蛋白主名 其他名称

ragulator complex protein LAMTOR1

RhoA activator C11orf59

重组 LAMTOR1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71583 LAMTOR1 Protein, Human (His) Q6IAA8 (2G-161P) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LAMTOR1 RGD RGD:735078
Bos taurus LAMTOR1 VGNC VGNC:30779
Felis catus LAMTOR1 VGNC VGNC:82041
Canis familiaris LAMTOR1 VGNC VGNC:42577
Macaca mulatta LAMTOR1 VGNC VGNC:74129
Mus musculus LAMTOR1 MGD MGI:1913758
Others LAMTOR1 NCBI