ANKZF1 - ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 Gene

中文名称：锚蛋白重复序列和锌指肽基 tRNA 水解酶 1

种属: Homo sapiens

同用名: Vms1; ZNF744

基因 ID: 55139 | 基因类型: protein coding

关于 ANKZF1

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:219,229,806-219,236,679 (from NCBI)

This gene has 26 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in lymph node (RPKM 19.0), spleen (RPKM 18.7) and 25 other tissues.

功能概要

预测可启用金属离子结合活性。参与细胞对过氧化氢的反应。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable metal ion binding activity. Involved in cellular response to hydrogen peroxide. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANKZF1 基因产物(3)

mRNA	Protein	Name
NM_001042410.2	NP_001035869.1	ankyrin repeat and zinc finger domain-containing protein 1 isoform 1
NM_001282792.2	NP_001269721.1	ankyrin repeat and zinc finger domain-containing protein 1 isoform 2
NM_018089.3	NP_060559.2	ankyrin repeat and zinc finger domain-containing protein 1 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA endonuclease activity	IDA IDA: 通过直接分析推断	30244831	GOA
enables catalytic activity, acting on a tRNA	IDA IDA: 通过直接分析推断	30244831	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	22190034	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cellular response to hydrogen peroxide	IMP IMP: 通过突变表型推断	28302725	GOA
involved in protein quality control for misfolded or incompletely synthesized proteins	IDA IDA: 通过直接分析推断	29632312	GOA
involved in rescue of stalled ribosome	IDA IDA: 通过直接分析推断	29632312	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	28302725	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ANKZF1 蛋白结构

Ank

0
200
400
600
726 a.a.

蛋白主名

其他名称

ankyrin repeat and zinc finger domain-containing protein 1

ankyrin repeat and zinc finger domain containing 1

关联疾病

疾病名称

别名

Immunodeficiency 40

Dock2 Deficiency	IMD40
Immunodeficiency, Type 40

Charcot-Marie-Tooth Disease, Axonal, Type 2e

Charcot-Marie-Tooth Disease Type 2	CMT2E
CMT2S	CMT2Y
Charcot-Marie-Tooth Disease Type 2e	Charcot-Marie-Tooth Disease Type 2y
Charcot-Marie-Tooth Disease Axonal Type 2s	Charcot-Marie-Tooth Disease, Axonal, Type 2s
Charcot-Marie-Tooth Disease, Type 2e	Hereditary Motor And Sensory Neuropathy Type 2
Charcot-Marie-Tooth Neuropathy, Type 2s	Charcot-Marie-Tooth Disease, Axonal, Autosomal Recessive, Type 2s
Charcot-Marie-Tooth Disease, Axonal, Type 2y	Charcot-Marie-Tooth Disease, Axonal, Autosomal Dominant, Type 2y
Charcot-Marie-Tooth Neuropathy, Type 2y	Charcot-Marie-Tooth Disease, Type 2y
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2e	Charcot-Marie-Tooth Neuropathy Type 2e
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 Due To Vcp Mutation	Cmt2 Due To Vcp Mutation
Charcot-Marie-Tooth Disease Type 2s	Autosomal Dominant Charcot-Marie-Tooth Disease Type 2
Autosomal Dominant Axonal Charcot-Marie-Tooth Disease	Cmt2
Charcot-Marie-Tooth Neuropathy, Type 2e	Hereditary Motor And Sensory Neuropathy Guadalajara Neuronal Type
Hereditary Motor And Sensory Neuropathy Okinawa Type	Autosomal Dominant Axonal Charcot-Marie-Tooth Type 2y
Charcot-Marie-Tooth Neuropathy Type 2y	Autosomal Recessive Axonal Charcot-Marie-Tooth Type 2s
Charcot-Marie-Tooth Neuropathy Type 2s	Charcot-Marie-Tooth Type 2
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2y	Charcot-Marie-Tooth Disease 2e
Charcot-Marie-Tooth Disease Axonal Type 2e	Charcot-Marie-Tooth Disease Neuronal Type 2e
Charcot-Marie-Tooth Disease 2s	Charcot-Marie-Tooth Neuropathy Axonal Type 2s
Charcot-Marie-Tooth Disease 2y	Charcot-Marie-Tooth Disease, Type 2
Hereditary Motor And Sensory-Neuropathy Type Ii

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS00738	ANKZF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	ANKZF1	VGNC	VGNC:69697
Rattus norvegicus	ANKZF1	RGD	RGD:1359242
Felis catus	ANKZF1	VGNC	VGNC:59825
Mus musculus	ANKZF1	MGD	MGI:1098746
Canis familiaris	ANKZF1	VGNC	VGNC:37921
Bos taurus	ANKZF1	VGNC	VGNC:25949

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ANKZF1 - ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 Gene

关于 ANKZF1

功能概要

ANKZF1 基因产物(3)

ANKZF1 蛋白结构

关联疾病

直系同源

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ANKZF1 - ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 Gene

关于 ANKZF1

功能概要

ANKZF1 基因产物(3)

ANKZF1 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z