1. Gene
  2. MRPS10 - mitochondrial ribosomal protein S10 Gene

MRPS10 - mitochondrial ribosomal protein S10 Gene

中文名称:线粒体核糖体蛋白 S10

种属: Homo sapiens

同用名: MRP-S10; PNAS-122

基因 ID: 55173 | 基因类型: protein coding

关于 MRPS10

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:42,206,807-42,217,861 (from NCBI)

This gene has 1 transcript (splice variant) and 203 orthologues. Ubiquitous expression in esophagus (RPKM 21.1), heart (RPKM 17.6) and 25 other tissues.

功能概要

哺乳动物线粒体核糖体蛋白由核基因编码,有助于线粒体内的蛋白质合成。线粒体核糖体 (线粒体核糖体) 由一个小的 28S 亚基和一个大的 39S 亚基组成。与原核核糖体相比,它们估计有 75% 的蛋白质与 rRNA 组成,而原核核糖体的比例是相反的。哺乳动物 线粒体核糖体 和原核核糖体之间的另一个区别是后者包含 5S rRNA。在不同的物种中,构成核糖体的蛋白质在序列上有很大差异,有时在生化特性上也有很大差异,这使得序列同源性难以识别。该基因编码属于核糖体蛋白 S10P 家族的 28S 亚基蛋白。对应于该基因的假基因位于染色体 1q、3p 和 9p 上。[RefSeq 提供,2008 年 7 月]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008]

MRPS10 基因产物(1)

mRNA Protein Name
NM_018141.4 NP_060611.2 28S ribosomal protein S10, mitochondrial

MRPS10 蛋白结构

Ribosomal_S10

Ribosomal_S10: Ribosomal protein S10p/S20e (78 - 173)

  • 0
  • 100
  • 201 a.a.
蛋白主名 其他名称

28S ribosomal protein S10, mitochondrial

S10mt

关联疾病

疾病名称 别名
Plethora Of Newborn

Neonatal Polycythemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus MRPS10 MGD MGI:1928139
Felis catus MRPS10 VGNC VGNC:102466
Canis familiaris MRPS10 VGNC VGNC:43408
Rattus norvegicus MRPS10 RGD RGD:1311516
Bos taurus MRPS10 VGNC VGNC:31654