2. Gene
  3. CSGALNACT1 - chondroitin sulfate N-acetylgalactosaminyltransferase 1 Gene

CSGALNACT1 - chondroitin sulfate N-acetylgalactosaminyltransferase 1 Gene

  • 基因
  • 蛋白
  • 相关产品

种属: Homo sapiens (human)

同用名: ChGn; ChGn-1; SDJLABA; CSGalNAcT-1; beta4GalNAcT

基因 ID: 55790 | 基因类型: protein coding

关于 CSGALNACT1

功能概要

This gene encodes an enzyme that transfers N-acetylglucosamine (GalNAc) to the core tetrasaccharide linker and to elongating chondroitin sulfate chains in proteoglycans. Knockout of the orthologous mouse gene indicates that the protein is necessary for normal cartilage development and aggrecan metabolism. Mutations in this gene are associated with multiple sclerosis progression, and with mild skeletal dysplasia and joint laxity. [provided by RefSeq, Aug 2017]

CSGALNACT1 基因产物(1)

mRNA Protein Name
NM_001354476.2 NP_001341405.1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
11514575 GOA
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
12163485 GOA
enables glucuronosyltransferase activity IDA
IDA: 通过直接分析推断
11514575 GOA
enables glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
12163485 GOA
enables peptidoglycan glycosyltransferase activity IDA
IDA: 通过直接分析推断
11514575 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in UDP-N-acetylgalactosamine metabolic process IDA
IDA: 通过直接分析推断
11514575 GOA
involved in UDP-glucuronate metabolic process IDA
IDA: 通过直接分析推断
11514575 GOA
involved in chondroitin sulfate biosynthetic process IDA
IDA: 通过直接分析推断
11514575 GOA
involved in chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IDA
IDA: 通过直接分析推断
12163485 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

chondroitin sulfate N-acetylgalactosaminyltransferase 1

beta4GalNAcT-1

chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1

chondroitin beta1,4 N-acetylgalactosaminyltransferase

glucuronylgalactosylproteoglycan 4-beta-N- acetylgalactosaminyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5045 Fmoc-Thr(GalNAc(Ac)3-β-D)-OH / 否
HY-RS16407 CSGALNACT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21280 Csgalnact1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
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